7AZY

Context-specific inhibition of eukaryotic translation by macrolide antibiotics

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000027	biological_process	ribosomal large subunit assembly
A	0002181	biological_process	cytoplasmic translation
A	0003723	molecular_function	RNA binding
A	0003735	molecular_function	structural constituent of ribosome
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005840	cellular_component	ribosome
A	0006412	biological_process	translation
A	0022625	cellular_component	cytosolic large ribosomal subunit
A	1990904	cellular_component	ribonucleoprotein complex
B	0002181	biological_process	cytoplasmic translation
B	0003735	molecular_function	structural constituent of ribosome
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0022625	cellular_component	cytosolic large ribosomal subunit
B	0030687	cellular_component	preribosome, large subunit precursor
B	0042254	biological_process	ribosome biogenesis
B	1990904	cellular_component	ribonucleoprotein complex
C	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C	0000470	biological_process	maturation of LSU-rRNA
C	0002181	biological_process	cytoplasmic translation
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005840	cellular_component	ribosome
C	0022625	cellular_component	cytosolic large ribosomal subunit
C	0042273	biological_process	ribosomal large subunit biogenesis
C	1990904	cellular_component	ribonucleoprotein complex
D	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D	0002181	biological_process	cytoplasmic translation
D	0003729	molecular_function	mRNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0022625	cellular_component	cytosolic large ribosomal subunit
D	0030687	cellular_component	preribosome, large subunit precursor
D	1990904	cellular_component	ribonucleoprotein complex
H	0002181	biological_process	cytoplasmic translation
H	0003723	molecular_function	RNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0015934	cellular_component	large ribosomal subunit
H	0022625	cellular_component	cytosolic large ribosomal subunit
H	0022626	cellular_component	cytosolic ribosome
H	1990904	cellular_component	ribonucleoprotein complex
I	0000027	biological_process	ribosomal large subunit assembly
I	0002181	biological_process	cytoplasmic translation
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005515	molecular_function	protein binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0019843	molecular_function	rRNA binding
I	0022625	cellular_component	cytosolic large ribosomal subunit
I	0030687	cellular_component	preribosome, large subunit precursor
I	1990904	cellular_component	ribonucleoprotein complex
M	0002181	biological_process	cytoplasmic translation
M	0003735	molecular_function	structural constituent of ribosome
M	0005515	molecular_function	protein binding
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0022625	cellular_component	cytosolic large ribosomal subunit
M	1990904	cellular_component	ribonucleoprotein complex
N	0000027	biological_process	ribosomal large subunit assembly
N	0000470	biological_process	maturation of LSU-rRNA
N	0002181	biological_process	cytoplasmic translation
N	0003723	molecular_function	RNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0005730	cellular_component	nucleolus
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0016236	biological_process	macroautophagy
N	0022625	cellular_component	cytosolic large ribosomal subunit
N	0032991	cellular_component	protein-containing complex
N	0042273	biological_process	ribosomal large subunit biogenesis
N	1990904	cellular_component	ribonucleoprotein complex
O	0002181	biological_process	cytoplasmic translation
O	0003735	molecular_function	structural constituent of ribosome
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0022625	cellular_component	cytosolic large ribosomal subunit
O	1990904	cellular_component	ribonucleoprotein complex
P	0000027	biological_process	ribosomal large subunit assembly
P	0000055	biological_process	ribosomal large subunit export from nucleus
P	0002181	biological_process	cytoplasmic translation
P	0003735	molecular_function	structural constituent of ribosome
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0008270	molecular_function	zinc ion binding
P	0016567	biological_process	protein ubiquitination
P	0019941	biological_process	modification-dependent protein catabolic process
P	0022625	cellular_component	cytosolic large ribosomal subunit
P	0022626	cellular_component	cytosolic ribosome
P	0031386	molecular_function	protein tag activity
P	0042254	biological_process	ribosome biogenesis
P	1990904	cellular_component	ribonucleoprotein complex
Q	0002181	biological_process	cytoplasmic translation
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0008270	molecular_function	zinc ion binding
Q	0022625	cellular_component	cytosolic large ribosomal subunit
Q	0044391	cellular_component	ribosomal subunit
Q	0046677	biological_process	response to antibiotic
Q	0046898	biological_process	response to cycloheximide
Q	1990904	cellular_component	ribonucleoprotein complex
R	0000470	biological_process	maturation of LSU-rRNA
R	0002181	biological_process	cytoplasmic translation
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0022625	cellular_component	cytosolic large ribosomal subunit
R	0180023	biological_process	cytosolic large ribosomal subunit assembly
R	1990904	cellular_component	ribonucleoprotein complex
S	0002181	biological_process	cytoplasmic translation
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005634	cellular_component	nucleus
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0015934	cellular_component	large ribosomal subunit
S	0022625	cellular_component	cytosolic large ribosomal subunit
S	1990904	cellular_component	ribonucleoprotein complex
U	0002181	biological_process	cytoplasmic translation
U	0003735	molecular_function	structural constituent of ribosome
U	0005515	molecular_function	protein binding
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0008270	molecular_function	zinc ion binding
U	0022625	cellular_component	cytosolic large ribosomal subunit
U	0044391	cellular_component	ribosomal subunit
U	0046872	molecular_function	metal ion binding
U	1990904	cellular_component	ribonucleoprotein complex
V	0000470	biological_process	maturation of LSU-rRNA
V	0002181	biological_process	cytoplasmic translation
V	0003723	molecular_function	RNA binding
V	0003729	molecular_function	mRNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005730	cellular_component	nucleolus
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0015934	cellular_component	large ribosomal subunit
V	0017148	biological_process	negative regulation of translation
V	0022625	cellular_component	cytosolic large ribosomal subunit
V	1990904	cellular_component	ribonucleoprotein complex
W	0002181	biological_process	cytoplasmic translation
W	0003735	molecular_function	structural constituent of ribosome
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0022625	cellular_component	cytosolic large ribosomal subunit
W	1990904	cellular_component	ribonucleoprotein complex
b	0000470	biological_process	maturation of LSU-rRNA
b	0002181	biological_process	cytoplasmic translation
b	0003723	molecular_function	RNA binding
b	0003735	molecular_function	structural constituent of ribosome
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0005840	cellular_component	ribosome
b	0006364	biological_process	rRNA processing
b	0022625	cellular_component	cytosolic large ribosomal subunit
b	0042254	biological_process	ribosome biogenesis
b	1990904	cellular_component	ribonucleoprotein complex
c	0002181	biological_process	cytoplasmic translation
c	0003735	molecular_function	structural constituent of ribosome
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0022625	cellular_component	cytosolic large ribosomal subunit
c	0070180	molecular_function	large ribosomal subunit rRNA binding
c	1990904	cellular_component	ribonucleoprotein complex
d	0000470	biological_process	maturation of LSU-rRNA
d	0002181	biological_process	cytoplasmic translation
d	0003723	molecular_function	RNA binding
d	0003735	molecular_function	structural constituent of ribosome
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
d	0022625	cellular_component	cytosolic large ribosomal subunit
d	0180023	biological_process	cytosolic large ribosomal subunit assembly
d	1990904	cellular_component	ribonucleoprotein complex
e	0002181	biological_process	cytoplasmic translation
e	0003735	molecular_function	structural constituent of ribosome
e	0005515	molecular_function	protein binding
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
e	0019843	molecular_function	rRNA binding
e	0022625	cellular_component	cytosolic large ribosomal subunit
e	1990904	cellular_component	ribonucleoprotein complex
f	0002181	biological_process	cytoplasmic translation
f	0003723	molecular_function	RNA binding
f	0003729	molecular_function	mRNA binding
f	0003735	molecular_function	structural constituent of ribosome
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0005840	cellular_component	ribosome
f	0006413	biological_process	translational initiation
f	0006414	biological_process	translational elongation
f	0015934	cellular_component	large ribosomal subunit
f	0022625	cellular_component	cytosolic large ribosomal subunit
f	0022626	cellular_component	cytosolic ribosome
f	1990904	cellular_component	ribonucleoprotein complex
g	0000448	biological_process	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
g	0002181	biological_process	cytoplasmic translation
g	0003723	molecular_function	RNA binding
g	0003735	molecular_function	structural constituent of ribosome
g	0005515	molecular_function	protein binding
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
g	0008270	molecular_function	zinc ion binding
g	0019843	molecular_function	rRNA binding
g	0022625	cellular_component	cytosolic large ribosomal subunit
g	0030687	cellular_component	preribosome, large subunit precursor
g	0046872	molecular_function	metal ion binding
g	1990904	cellular_component	ribonucleoprotein complex
h	0000027	biological_process	ribosomal large subunit assembly
h	0002181	biological_process	cytoplasmic translation
h	0003723	molecular_function	RNA binding
h	0003735	molecular_function	structural constituent of ribosome
h	0005634	cellular_component	nucleus
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0005840	cellular_component	ribosome
h	0006412	biological_process	translation
h	0019843	molecular_function	rRNA binding
h	0022625	cellular_component	cytosolic large ribosomal subunit
h	1990904	cellular_component	ribonucleoprotein complex
j	0002181	biological_process	cytoplasmic translation
j	0003735	molecular_function	structural constituent of ribosome
j	0005515	molecular_function	protein binding
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0005840	cellular_component	ribosome
j	0006412	biological_process	translation
j	0022618	biological_process	protein-RNA complex assembly
j	0022625	cellular_component	cytosolic large ribosomal subunit
j	1990904	cellular_component	ribonucleoprotein complex
k	0002181	biological_process	cytoplasmic translation
k	0003723	molecular_function	RNA binding
k	0003735	molecular_function	structural constituent of ribosome
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0005840	cellular_component	ribosome
k	0006412	biological_process	translation
k	0022625	cellular_component	cytosolic large ribosomal subunit
k	1990904	cellular_component	ribonucleoprotein complex
l	0000027	biological_process	ribosomal large subunit assembly
l	0002181	biological_process	cytoplasmic translation
l	0003723	molecular_function	RNA binding
l	0003735	molecular_function	structural constituent of ribosome
l	0005515	molecular_function	protein binding
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0005840	cellular_component	ribosome
l	0006364	biological_process	rRNA processing
l	0006412	biological_process	translation
l	0006414	biological_process	translational elongation
l	0022625	cellular_component	cytosolic large ribosomal subunit
l	1990145	biological_process	maintenance of translational fidelity
l	1990904	cellular_component	ribonucleoprotein complex
m	0002181	biological_process	cytoplasmic translation
m	0003723	molecular_function	RNA binding
m	0003735	molecular_function	structural constituent of ribosome
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0005840	cellular_component	ribosome
m	0006412	biological_process	translation
m	0022625	cellular_component	cytosolic large ribosomal subunit
m	1990904	cellular_component	ribonucleoprotein complex
n	0002181	biological_process	cytoplasmic translation
n	0003735	molecular_function	structural constituent of ribosome
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0005840	cellular_component	ribosome
n	0006412	biological_process	translation
n	0006450	biological_process	regulation of translational fidelity
n	0022625	cellular_component	cytosolic large ribosomal subunit
n	1990904	cellular_component	ribonucleoprotein complex
o	0000027	biological_process	ribosomal large subunit assembly
o	0002181	biological_process	cytoplasmic translation
o	0003735	molecular_function	structural constituent of ribosome
o	0005515	molecular_function	protein binding
o	0005737	cellular_component	cytoplasm
o	0005829	cellular_component	cytosol
o	0005840	cellular_component	ribosome
o	0006412	biological_process	translation
o	0006415	biological_process	translational termination
o	0022625	cellular_component	cytosolic large ribosomal subunit
o	1990904	cellular_component	ribonucleoprotein complex
p	0002181	biological_process	cytoplasmic translation
p	0003723	molecular_function	RNA binding
p	0003735	molecular_function	structural constituent of ribosome
p	0005634	cellular_component	nucleus
p	0005737	cellular_component	cytoplasm
p	0005829	cellular_component	cytosol
p	0005840	cellular_component	ribosome
p	0006412	biological_process	translation
p	0022625	cellular_component	cytosolic large ribosomal subunit
p	1990904	cellular_component	ribonucleoprotein complex
q	0002181	biological_process	cytoplasmic translation
q	0003723	molecular_function	RNA binding
q	0003735	molecular_function	structural constituent of ribosome
q	0005737	cellular_component	cytoplasm
q	0005829	cellular_component	cytosol
q	0005840	cellular_component	ribosome
q	0006412	biological_process	translation
q	0015934	cellular_component	large ribosomal subunit
q	0022625	cellular_component	cytosolic large ribosomal subunit
q	0032991	cellular_component	protein-containing complex
q	0042273	biological_process	ribosomal large subunit biogenesis
q	1990904	cellular_component	ribonucleoprotein complex
r	0002181	biological_process	cytoplasmic translation
r	0003735	molecular_function	structural constituent of ribosome
r	0005737	cellular_component	cytoplasm
r	0005829	cellular_component	cytosol
r	0005840	cellular_component	ribosome
r	0006412	biological_process	translation
r	0022625	cellular_component	cytosolic large ribosomal subunit
r	1990904	cellular_component	ribonucleoprotein complex
s	0002181	biological_process	cytoplasmic translation
s	0003735	molecular_function	structural constituent of ribosome
s	0005737	cellular_component	cytoplasm
s	0005829	cellular_component	cytosol
s	0005840	cellular_component	ribosome
s	0006412	biological_process	translation
s	0015934	cellular_component	large ribosomal subunit
s	0022625	cellular_component	cytosolic large ribosomal subunit
s	1990904	cellular_component	ribonucleoprotein complex
t	0000027	biological_process	ribosomal large subunit assembly
t	0002181	biological_process	cytoplasmic translation
t	0003723	molecular_function	RNA binding
t	0003735	molecular_function	structural constituent of ribosome
t	0005515	molecular_function	protein binding
t	0005634	cellular_component	nucleus
t	0005737	cellular_component	cytoplasm
t	0005829	cellular_component	cytosol
t	0005840	cellular_component	ribosome
t	0006412	biological_process	translation
t	0008097	molecular_function	5S rRNA binding
t	0019843	molecular_function	rRNA binding
t	0022625	cellular_component	cytosolic large ribosomal subunit
t	0022626	cellular_component	cytosolic ribosome
t	1990904	cellular_component	ribonucleoprotein complex
u	0002181	biological_process	cytoplasmic translation
u	0003735	molecular_function	structural constituent of ribosome
u	0005737	cellular_component	cytoplasm
u	0005829	cellular_component	cytosol
u	0005840	cellular_component	ribosome
u	0006412	biological_process	translation
u	0015934	cellular_component	large ribosomal subunit
u	0022625	cellular_component	cytosolic large ribosomal subunit
u	1990904	cellular_component	ribonucleoprotein complex
v	0000027	biological_process	ribosomal large subunit assembly
v	0002181	biological_process	cytoplasmic translation
v	0003735	molecular_function	structural constituent of ribosome
v	0005737	cellular_component	cytoplasm
v	0005829	cellular_component	cytosol
v	0005840	cellular_component	ribosome
v	0006364	biological_process	rRNA processing
v	0006412	biological_process	translation
v	0022625	cellular_component	cytosolic large ribosomal subunit
v	0042273	biological_process	ribosomal large subunit biogenesis
v	1990904	cellular_component	ribonucleoprotein complex
w	0002181	biological_process	cytoplasmic translation
w	0003723	molecular_function	RNA binding
w	0003735	molecular_function	structural constituent of ribosome
w	0005515	molecular_function	protein binding
w	0005737	cellular_component	cytoplasm
w	0005829	cellular_component	cytosol
w	0005840	cellular_component	ribosome
w	0006412	biological_process	translation
w	0022625	cellular_component	cytosolic large ribosomal subunit
w	1990904	cellular_component	ribonucleoprotein complex
x	0002181	biological_process	cytoplasmic translation
x	0003723	molecular_function	RNA binding
x	0003735	molecular_function	structural constituent of ribosome
x	0005737	cellular_component	cytoplasm
x	0005829	cellular_component	cytosol
x	0005840	cellular_component	ribosome
x	0006412	biological_process	translation
x	0019843	molecular_function	rRNA binding
x	0022625	cellular_component	cytosolic large ribosomal subunit
x	0042273	biological_process	ribosomal large subunit biogenesis
x	1990145	biological_process	maintenance of translational fidelity
x	1990904	cellular_component	ribonucleoprotein complex
y	0000448	biological_process	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
y	0002181	biological_process	cytoplasmic translation
y	0003735	molecular_function	structural constituent of ribosome
y	0005737	cellular_component	cytoplasm
y	0005829	cellular_component	cytosol
y	0005840	cellular_component	ribosome
y	0006412	biological_process	translation
y	0015934	cellular_component	large ribosomal subunit
y	0022625	cellular_component	cytosolic large ribosomal subunit
y	0030687	cellular_component	preribosome, large subunit precursor
y	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AIVVrqakswrrr.DGvflyFedNagVI

Chain	Residue	Details
c	ALA76-ILE102

---

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLTadydaldI

Chain	Residue	Details
I	LYS120-ILE135

---

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. RTnntIryNakrRNWRR

Chain	Residue	Details
M	ARG30-ARG46

---

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KskIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
P	LYS27-ASP52

---

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLSGQtpVqSkARyT

Chain	Residue	Details
h	LEU37-THR53

---

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinkyesspSHIELvV

Chain	Residue	Details
y	ARG126-VAL150

---

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PktRGVAmNPvD

Chain	Residue	Details
x	PRO197-ASP208

---

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FeqnemiDaiAvTkGHGfeGvthR

Chain	Residue	Details
l	PHE209-ARG232

---

site_id	PS00475
Number of Residues	32
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KILGkGrIpnvp.ViVkarfVSklAeekIraaG

Chain	Residue	Details
S	LYS111-GLY142

---

site_id	PS00526
Number of Residues	20
Details	RIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaAsvvgVGkrkVWLDP

Chain	Residue	Details
H	GLN7-PRO26

---

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. SLPKIKtVRKSIACV

Chain	Residue	Details
D	SER40-VAL54

---

site_id	PS00580
Number of Residues	21
Details	RIBOSOMAL_L32E Ribosomal protein L32e signature. FkRhhsdRyhRVaen..WRKqkG

Chain	Residue	Details
r	PHE17-GLY37

---

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. VLqlLrLtRinSgTfvkvtkatleLLklIepYV

Chain	Residue	Details
C	VAL102-VAL134

---

site_id	PS00700
Number of Residues	22
Details	RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QicrVrnKdiRkFlDGIYVshK

Chain	Residue	Details
e	GLN163-LYS184

---

site_id	PS00783
Number of Residues	24
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. LRGMVShktarGKaalerLkVFeG

Chain	Residue	Details
V	LEU84-GLY107

---

site_id	PS00939
Number of Residues	27
Details	RIBOSOMAL_L1E Ribosomal protein L1e signature. NhneKryATaSAIaATAvaslvlaRGH

Chain	Residue	Details
p	ASN114-HIS140

---

site_id	PS01073
Number of Residues	18
Details	RIBOSOMAL_L24E Ribosomal protein L24e signature. FsGakIyPGrGtlFvRgD

Chain	Residue	Details
f	PHE8-ASP25

---

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTpSfGkRhnks.HtlCnRCG

Chain	Residue	Details
g	GLY4-GLY23

---

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CkkmgVPYaiVkGKarLG

Chain	Residue	Details
b	CYS170-GLY187

---

site_id	PS01104
Number of Residues	15
Details	RIBOSOMAL_L13E Ribosomal protein L13e signature. RaGRGFTLaEVkaaG

Chain	Residue	Details
k	ARG70-GLY84

---

site_id	PS01105
Number of Residues	22
Details	RIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRtHGnsGvVrAtFrnnLP

Chain	Residue	Details
v	GLY69-PRO90

---

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. KaLflSKinRPpVSVsRI

Chain	Residue	Details
m	LYS50-ILE67

---

site_id	PS01107
Number of Residues	12
Details	RIBOSOMAL_L27E Ribosomal protein L27e signature. GKNqWFFskLRF

Chain	Residue	Details
O	GLY125-PHE136

---

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVlVVrGskKGqe.GkI

Chain	Residue	Details
q	ASP53-ILE70

---

site_id	PS01144
Number of Residues	15
Details	RIBOSOMAL_L31E Ribosomal protein L31e signature. VRLApeLNqAiWkRG

Chain	Residue	Details
n	VAL49-GLY63

---

site_id	PS01145
Number of Residues	14
Details	RIBOSOMAL_L34E Ribosomal protein L34e signature. TrSnKikvvKTPGG

Chain	Residue	Details
B	THR15-GLY28

---

site_id	PS01170
Number of Residues	19
Details	RIBOSOMAL_L6E Ribosomal protein L6e signature. NgvPLRRvnarYVIATSt.K

Chain	Residue	Details
A	ASN72-LYS90

---

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikangsiqk.GmpHkfYqGkTG

Chain	Residue	Details
u	GLY37-GLY62

---

site_id	PS01172
Number of Residues	12
Details	RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKvvLRleC

Chain	Residue	Details
Q	LYS63-CYS74

---

site_id	PS01190
Number of Residues	11
Details	RIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRlIDLIR

Chain	Residue	Details
d	PRO52-ARG62

---

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGFVIYRvRVrRG

Chain	Residue	Details
R	ASP46-GLY69

---

site_id	PS01257
Number of Residues	22
Details	RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqqGMRgAWGKPhGlaARV

Chain	Residue	Details
o	ALA107-VAL128

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"16096273","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"N6,N6-dimethyllysine; by RKM1","evidences":[{"source":"PubMed","id":"17327221","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N-acetylthreonine","evidences":[{"source":"PubMed","id":"10601260","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P24000","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	18
Details	Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22096102","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Modified residue: {"description":"N6,N6,N6-trimethyllysine","evidences":[{"source":"PubMed","id":"22522802","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)","evidences":[{"source":"PubMed","id":"15542864","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P40212","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	47
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	37
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine; by RKM3","evidences":[{"source":"PubMed","id":"18957409","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22522802","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24517342","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine; by RKM4","evidences":[{"source":"PubMed","id":"18957409","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24517342","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	73
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	12
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"source":"PubMed","id":"2104804","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	21
Details	Zinc finger: {"description":"C4-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	9
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	9
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	1
Details	Modified residue: {"description":"Pros-methylhistidine","evidences":[{"source":"PubMed","id":"20864530","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24865971","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26826131","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	14
Details	Repeat: {"description":"1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	16
Details	Repeat: {"description":"2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	49
Details	Region: {"description":"2 X 15-17 AA approximate repeats"}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	85
Details	Region: {"description":"C-terminal-extended nuclear localization signal","evidences":[{"source":"PubMed","id":"25936803","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"1544921","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	1
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"PubMed","id":"26046779","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"Q12672","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine; partial","evidences":[{"source":"PubMed","id":"10601260","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"10601260","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---