4UG0

STRUCTURE OF THE HUMAN 80S RIBOSOME

This is a large structure.

Summary for 4UG0

EMDB information2938
Descriptor28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ... (83 entities in total)
Functional Keywordsribosome
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm  P62917 P40429 Q07020 P83881 P61247 P23396 P62701 P62241 P46783 P62269 P60866 P46781
Nucleus, nucleolus  P39023 P62913
Cytoplasm {ECO:0000269|PubMed:15469983, ECO:0000269|Ref P46777
Membrane ; Lipid-anchor  P61313
Ubiquitin: Cytoplasm . 60S ribosomal protein L40: Cytoplasm  P62987
Cell membrane P08865
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome  P62081
Nucleus  P39019
Ubiquitin: Cytoplasm  P62979
Cell membrane ; Peripheral membrane protein P63244
Total number of polymer chains81
Total molecular weight3835516.96
Authors
Khatter, H.,Myasnikov, A.G.,Natchiar, S.K.,Klaholz, B.P. (deposition date: 2015-03-20, release date: 2015-06-10, Last modification date: 2018-02-14)
Primary citation
Khatter, K.,Mysanikov, A.G.,Natchiar, S.K.,Klaholz, B.P.
Structure of the human 80S ribosome
NATURE, 520:640-645, 2015
PubMed: 25901680 (PDB entries with the same primary citation)
DOI: 10.1038/nature14427
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone155.0%0.0%0.40MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 4ug0
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Molmil generated image of 4ug0
rotated about x axis by 90°
Molmil generated image of 4ug0
rotated about y axis by 90°