3J79

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, large subunit

This is a large structure.

Summary for 3J79

Related3J7A
Integrates1VX6 1VX7
EMDB informationEMD-2660 EMD-2661
Descriptor28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ... (47 entities in total)
Functional Keywordsemetine, ribosome-inhibitor complex, ribosome/inhibitor
Biological sourcePlasmodium falciparum
Total number of polymer chains45
Total molecular weight2135888.8
Authors
Wong, W.,Bai, X.C.,Brown, A.,Fernandez, I.S.,Hanssen, E.,Condron, M.,Tan, Y.H.,Baum, J.,Scheres, S.H.W. (deposition date: 2014-06-02, release date: 2014-07-16, Last modification date: 2015-06-03)
Primary citation
Wong, W.,Bai, X.C.,Brown, A.,Fernandez, I.S.,Hanssen, E.,Condron, M.,Tan, Y.H.,Baum, J.,Scheres, S.H.
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3:e03080-e03080, 2014
PubMed: 24913268 (PDB entries with the same primary citation)
DOI: 10.7554/eLife.03080
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone42.4%10.6%0.43MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 3j79
no rotation
Molmil generated image of 3j79
rotated about x axis by 90°
Molmil generated image of 3j79
rotated about y axis by 90°
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