2VST
hPPARgamma Ligand binding domain in complex with 13-(S)-HODE
Summary for 2VST
Entry DOI | 10.2210/pdb2vst/pdb |
Related | 1FM6 1FM9 1I7I 1K74 1KNU 1NYX 1PRG 1RDT 1WM0 1ZGY 2F4B 2FVJ 2G0G 2G0H 2PRG 2VSR 2VV0 2VV1 2VV2 2VV3 2VV4 3PRG 4PRG |
Descriptor | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA, (9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid (3 entities in total) |
Functional Keywords | transcription regulation, alternative splicing, ligand binding domain, nuclear receptor, diabetes mellitus, zinc-finger, dna-binding, polymorphism, transcription, zinc, obesity, nucleus, receptor, activator, oxidised fatty acid, transcription factor, metal-binding, phosphoprotein, disease mutation |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus: P37231 |
Total number of polymer chains | 2 |
Total formula weight | 63491.93 |
Authors | Itoh, T.,Fairall, L.,Schwabe, J.W.R. (deposition date: 2008-04-29, release date: 2008-08-19, Last modification date: 2023-12-13) |
Primary citation | Itoh, T.,Fairall, L.,Amin, K.,Inaba, Y.,Szanto, A.,Balint, B.L.,Nagy, L.,Yamamoto, K.,Schwabe, J.W.R. Structural Basis for the Activation of Pparg by Oxidised Fatty Acids Nat.Struct.Mol.Biol., 15:924-, 2008 Cited by PubMed: 19172745DOI: 10.1038/NSMB.1474 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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