1PRG

LIGAND BINDING DOMAIN OF THE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA

Summary for 1PRG

DescriptorPROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA) (2 entities in total)
Functional Keywordsthiazolidinedione, ligand-binding domain, nuclear receptor, apo, transcription factor, orphan receptor, gene regulation
Biological sourceHomo sapiens (human)
Cellular locationNucleus P37231
Total number of polymer chains2
Total molecular weight61667.7
Authors
Nolte, R.T.,Wisely, G.B.,Milburn, M.V. (deposition date: 1998-07-02, release date: 2001-01-13, Last modification date: 2011-07-13)
Primary citation
Nolte, R.T.,Wisely, G.B.,Westin, S.,Cobb, J.E.,Lambert, M.H.,Kurokawa, R.,Rosenfeld, M.G.,Willson, T.M.,Glass, C.K.,Milburn, M.V.
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma.
Nature, 395:137-143, 1998
PubMed: 9744270 (PDB entries with the same primary citation)
DOI: 10.1038/25931
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.319323.9%3.5%6.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report