Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | LLL |
| Number of Residues | 16 |
| Details | THESE RESIDUES ARE INVOLVED IN BINDING THE LXXLL HELIX OF COACTIVATORS. |
| Chain | Residue |
| A | GLU471 |
| A | LYS301 |
| A | THR297 |
| A | GLN314 |
| A | VAL315 |
| A | LEU468 |
| A | LEU318 |
| A | LEU311 |
| B | GLU471 |
| B | LYS301 |
| B | THR297 |
| B | GLN314 |
| B | VAL315 |
| B | LEU468 |
| B | LEU318 |
| B | LEU311 |
| site_id | LND |
| Number of Residues | 22 |
| Details | THESE RESIDUES ARE INVOLVED IN LIGAND BINDING. |
| Chain | Residue |
| A | HIS323 |
| A | VAL339 |
| A | ILE341 |
| B | HIS323 |
| B | LEU469 |
| B | HIS449 |
| B | GLN286 |
| B | TYR327 |
| B | LEU330 |
| B | PHE282 |
| B | CYS285 |
| A | LEU469 |
| B | ARG288 |
| B | VAL339 |
| B | ILE341 |
| A | HIS449 |
| A | GLN286 |
| A | TYR327 |
| A | LEU330 |
| A | PHE282 |
| A | CYS285 |
| A | ARG288 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 530 |
| Details | Domain: {"description":"NR LBD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01189","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Motif: {"description":"9aaTAD","evidences":[{"source":"PubMed","id":"30468856","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9744270","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2PRG","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"36737649","evidenceCode":"ECO:0000269"}]} |
