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PDB: 296 results

4BVU
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BU of 4bvu by Molmil
Structure of Shigella effector OspG in complex with host UbcH5c- Ubiquitin conjugate
Descriptor: PROTEIN KINASE OSPG, UBIQUITIN, UBIQUITIN-CONJUGATING ENZYME E2 D3
Authors:Pruneda, J.N, LeTrong, I, Stenkamp, R.E, Klevit, R.E, Brzovic, P.S.
Deposit date:2013-06-28
Release date:2014-01-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:E2~Ub Conjugates Regulate the Kinase Activity of Shigella Effector Ospg During Pathogenesis.
Embo J., 33, 2014
3PTF
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BU of 3ptf by Molmil
X-ray structure of the non-covalent complex between UbcH5A and Ubiquitin
Descriptor: Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D1
Authors:Bosanac, I, Hymowitz, S.G.
Deposit date:2010-12-02
Release date:2011-05-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Modulation of K11-Linkage Formation by Variable Loop Residues within UbcH5A.
J.Mol.Biol., 408, 2011
1F9J
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BU of 1f9j by Molmil
STRUCTURE OF A NEW CRYSTAL FORM OF TETRAUBIQUITIN
Descriptor: TETRAUBIQUITIN
Authors:Phillips, C.L, Thrower, J, Pickart, C.M, Hill, C.P.
Deposit date:2000-07-10
Release date:2001-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of a new crystal form of tetraubiquitin.
Acta Crystallogr.,Sect.D, 57, 2001
3MTN
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BU of 3mtn by Molmil
Usp21 in complex with a ubiquitin-based, USP21-specific inhibitor
Descriptor: CHLORIDE ION, GLYCEROL, UBIQUITIN VARIANT UBV.21.4, ...
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2010-04-30
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
3DVN
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BU of 3dvn by Molmil
Crystal structure of K63-specific fab Apu2.16 bound to K63-linked di-ubiquitin
Descriptor: Human IgG1 fab fragment heavy chain, Human IgG1 fab fragment light chain, Ubiquitin, ...
Authors:Hymowitz, S.G.
Deposit date:2008-07-18
Release date:2008-09-30
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
Cell(Cambridge,Mass.), 134, 2008
3O65
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BU of 3o65 by Molmil
Crystal structure of a Josephin-ubiquitin complex: Evolutionary restraints on ataxin-3 deubiquitinating activity
Descriptor: Putative ataxin-3-like protein, SODIUM ION, Ubiquitin
Authors:Weeks, S.D, Grasty, K.C, Hernandez-Cuebas, L, Loll, P.J.
Deposit date:2010-07-28
Release date:2010-11-24
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of a Josephin-Ubiquitin Complex: EVOLUTIONARY RESTRAINTS ON ATAXIN-3 DEUBIQUITINATING ACTIVITY.
J.Biol.Chem., 286, 2011
3JSV
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BU of 3jsv by Molmil
Crystal structure of mouse NEMO CoZi in complex with Lys63-linked di-ubiquitin
Descriptor: NF-kappa-B essential modulator, Ubiquitin
Authors:Yoshikawa, A, Sato, Y, Mimura, H, Yamashita, M, Yamagata, A, Fukai, S.
Deposit date:2009-09-11
Release date:2009-10-27
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin
Febs Lett., 583, 2009
2HTH
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BU of 2hth by Molmil
Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain
Descriptor: Ubiquitin, Vacuolar protein sorting protein 36
Authors:Alam, S.L, Whitby, F.G, Hill, C.P, Sundquist, W.I.
Deposit date:2006-07-25
Release date:2006-10-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain.
Nat.Struct.Mol.Biol., 13, 2006
7BXG
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BU of 7bxg by Molmil
MavC-UBE2N-Ub complex
Descriptor: MavC, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N
Authors:Gao, P, Wang, Y.
Deposit date:2020-04-19
Release date:2020-05-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.705 Å)
Cite:Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors.
Nat Commun, 11, 2020
4MM3
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BU of 4mm3 by Molmil
Crystal structure of SARS-CoV papain-like protease PLpro in complex with ubiquitin aldehyde
Descriptor: Papain-like proteinase, Ubiquitin, ZINC ION
Authors:Mesecar, A.D, Ratia, K.
Deposit date:2013-09-08
Release date:2014-07-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.752 Å)
Cite:Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating activity of SARS-CoV papain-like protease.
Plos Pathog., 10, 2014
3VFK
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BU of 3vfk by Molmil
The structure of monodechloro-teicoplanin in complex with its ligand, using ubiquitin as a ligand carrier
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, 8-METHYLNONANOIC ACID, ...
Authors:Economou, N.J, Weeks, S.D, Grasty, K.C, Loll, P.J.
Deposit date:2012-01-09
Release date:2013-01-09
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the complex between teicoplanin and a bacterial cell-wall peptide: use of a carrier-protein approach.
Acta Crystallogr.,Sect.D, 69, 2013
6UMP
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BU of 6ump by Molmil
Crystal structure of MavC in complex with substrate mimic in P65 space group
Descriptor: MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N
Authors:Puvar, K, Iyer, S, Luo, Z.Q, Das, C.
Deposit date:2019-10-10
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
6S53
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BU of 6s53 by Molmil
Crystal structure of TRIM21 RING domain in complex with an isopeptide-linked Ube2N~ubiquitin conjugate
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, ...
Authors:Kiss, L, Boland, A, Neuhaus, D, James, L.C.
Deposit date:2019-06-30
Release date:2019-09-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.
Nat Commun, 10, 2019
3IHP
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BU of 3ihp by Molmil
Covalent Ubiquitin-Usp5 Complex
Descriptor: CHLORIDE ION, ETHANAMINE, Ubiquitin, ...
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2009-07-30
Release date:2009-12-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Covalent Ubiquitin-Usp5 Complex
To be Published
8A9J
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BU of 8a9j by Molmil
Cryo-EM structure of USP1-UAF1 bound to FANCI and mono-ubiquitinated FANCD2 without ML323 (consensus reconstruction)
Descriptor: DNA (61-MER), Fanconi anemia group D2 protein, Fanconi anemia group I protein, ...
Authors:Rennie, M.L, Walden, H.
Deposit date:2022-06-28
Release date:2022-10-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site.
Sci Adv, 8, 2022
3K9P
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BU of 3k9p by Molmil
The crystal structure of E2-25K and ubiquitin complex
Descriptor: Ubiquitin, Ubiquitin-conjugating enzyme E2 K
Authors:Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H.
Deposit date:2009-10-16
Release date:2010-09-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity
J.Biol.Chem., 285, 2010
3KVF
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BU of 3kvf by Molmil
Crystal structure of the I93M mutant of ubiquitin carboxy terminal hydrolase L1 bound to ubiquitin vinylmethylester
Descriptor: METHYL 4-AMINOBUTANOATE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase isozyme L1
Authors:Davies, C.W, Maiti, T.K, Das, C.
Deposit date:2009-11-30
Release date:2010-06-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation.
Proc.Natl.Acad.Sci.USA, 107, 2010
7R71
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BU of 7r71 by Molmil
Crystal Structure of the UbArk2C-UbcH5b~Ub complex
Descriptor: Ubiquitin, Ubiquitin,E3 ubiquitin-protein ligase RNF165, Ubiquitin-conjugating enzyme E2 D2, ...
Authors:Paluda, A, Middleton, A.J, Mace, P.D, Day, C.L.
Deposit date:2021-06-24
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C.
Nat Commun, 13, 2022
7UYH
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BU of 7uyh by Molmil
Structure of the first OTU domain from Legionella pneumophila effector protein LotA bound to K6-linked diUb
Descriptor: LotA, Ubiquitin
Authors:Warren, G.D, Pruneda, J.N.
Deposit date:2022-05-06
Release date:2022-12-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA.
Mol.Cell, 83, 2023
5OHV
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BU of 5ohv by Molmil
K33-specific affimer bound to K33 diUb
Descriptor: GLYCEROL, K33-specific affimer, SULFATE ION, ...
Authors:Michel, M.A, Komander, D.
Deposit date:2017-07-18
Release date:2017-10-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling.
Mol. Cell, 68, 2017
7NPI
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BU of 7npi by Molmil
Crystal structure of Mindy2 (C266A) in complex with Lys48-linked penta-ubiquitin (K48-Ub5)
Descriptor: CHLORIDE ION, Polyubiquitin-C, SODIUM ION, ...
Authors:Lange, S.M, Armstrong, L.A, Kulathu, Y.
Deposit date:2021-02-26
Release date:2021-09-15
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2.
Mol.Cell, 81, 2021
3KW5
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BU of 3kw5 by Molmil
Crystal structure of ubiquitin carboxy terminal hydrolase L1 bound to ubiquitin vinylmethylester
Descriptor: METHYL 4-AMINOBUTANOATE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase isozyme L1
Authors:Maiti, T.K, Boudreaux, D.A, Das, C.
Deposit date:2009-11-30
Release date:2010-06-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation.
Proc.Natl.Acad.Sci.USA, 107, 2010
4KSL
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BU of 4ksl by Molmil
Gumby/Fam105B in complex with linear di-ubiquitin
Descriptor: Polyubiquitin-C, Protein FAM105B
Authors:Juang, Y.-C, Ceccarelli, D.F, Sicheri, F.
Deposit date:2013-05-17
Release date:2013-06-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature, 498, 2013
5ZQ7
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BU of 5zq7 by Molmil
SidE-Ubi-NAD
Descriptor: ADENOSINE MONOPHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SidE, ...
Authors:Wang, Y, Gao, A, Gao, P.
Deposit date:2018-04-17
Release date:2018-05-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.847 Å)
Cite:Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
5E6J
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BU of 5e6j by Molmil
Structure of SARS PLpro bound to a Lys48-linked di-ubiquitin activity based probe
Descriptor: ACETATE ION, NICKEL (II) ION, Polyubiquitin-B, ...
Authors:Lima, C.D, Bekes, M.
Deposit date:2015-10-09
Release date:2016-05-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease.
Mol. Cell, 62, 2016

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数据于2024-07-10公开中

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