2VV0

hPPARgamma Ligand binding domain in complex with DHA

2VV0 の概要

• エントリーDOI: 10.2210/pdb2vv0/pdb
• 関連するPDBエントリー: 1FM6 1FM9 1I7I 1K74 1KNU 1NYX 1PRG 1RDT 1WM0 1ZGY 2F4B 2FVJ 2G0G 2G0H 2PRG 2VSR 2VST 2VV1 2VV2 2VV3 2VV4 3PRG 4PRG
• 分子名称: PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA, DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID (3 entities in total)
• 機能のキーワード: nuclear receptor, transcription regulation, alternative splicing, ligand binding domain, diabetes mellitus, zinc-finger, dna-binding, polymorphism, transcription, zinc, obesity, nucleus, receptor, activator, oxidised fatty acid, transcription factor, metal-binding, phosphoprotein, disease mutation
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 63556.02

構造登録者

Itoh, T.,Fairall, L.,Schwabe, J.W.R. (登録日: 2008-06-02, 公開日: 2008-08-19, 最終更新日: 2023-12-13)

• 主引用文献: Itoh, T.,Fairall, L.,Amin, K.,Inaba, Y.,Szanto, A.,Balint, B.L.,Nagy, L.,Yamamoto, K.,Schwabe, J.W.R.; Structural Basis for the Activation of Pparg by Oxidised Fatty Acids; Nat.Struct.Mol.Biol., 15:924-, 2008; PubMed: 19172745; DOI: 10.1038/NSMB.1474

実験手法

X-RAY DIFFRACTION (2.55 Å)