2Y8O

Crystal structure of human p38alpha complexed with a MAPK docking peptide

Summary for 2Y8O

Entry DOI	10.2210/pdb2y8o/pdb
Related	1A9U 1BL6 1BL7 1BMK 1DI9 1IAN 1KV1 1KV2 1M7Q 1OUK 1OUY 1OVE 1OZ1 1R39 1R3C 1W7H 1W82 1W83 1W84 1WBN 1WBO 1WBS 1WBT 1WBV 1WBW 1WFC 1YQJ 1ZYJ 1ZZ2 1ZZL 2BAJ 2BAK 2BAL 2BAQ 2I0H 2YIS 2YIW 2YIX 3ZS5 3ZSG 3ZSH 3ZSI 3ZYA 4AA0 4AA4 4AA5 4AAC
Descriptor	MITOGEN-ACTIVATED PROTEIN KINASE 14, DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6 (3 entities in total)
Functional Keywords	transferase, signalling, map kinase pathway, protein-protein interaction
Biological source	Homo sapiens (HUMAN) More
Cellular location	Cytoplasm : Q16539 Nucleus : P52564
Total number of polymer chains	2
Total formula weight	43028.20
Authors	Barkai, T.,Garai, A.,Toeroe, I.,Remenyi, A. (deposition date: 2011-02-08, release date: 2012-02-22, Last modification date: 2023-12-20)
Primary citation	Garai, A.,Zeke, A.,Gogl, G.,Toro, I.,Fordos, F.,Blankenburg, H.,Barkai, T.,Varga, J.,Alexa, A.,Emig, D.,Albrecht, M.,Remenyi, A. Specificity of Linear Motifs that Bind to a Common Mitogen-Activated Protein Kinase Docking Groove. Sci. Signal, 5:74-, 2012 Cited by PubMed: 23047924 DOI: 10.1126/SCISIGNAL.2003004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation