2Y8O
Crystal structure of human p38alpha complexed with a MAPK docking peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MITOGEN-ACTIVATED PROTEIN KINASE 14 | polymer | 362 | 41471.3 | 1 | UniProt (Q16539) Pfam (PF00069) | Homo sapiens (HUMAN) | CYTOKINE SUPPRESSIVE ANTI-INFLAMMATORY DRUG-BINDING PROTEIN, MAP KINASE MXI2, MAX-INTERACTING PROTEIN 2, MITOGEN-ACTIVATED PROTEIN KINASE P38 ALPHA |
| 2 | B (B) | DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6 | polymer | 14 | 1556.9 | 1 | UniProt (P52564) | HOMO SAPIENS | MAPK/ERK KINASE 6, SAPKK3 |
| 3 | C, D (A, B) | water | water | 18.0 | 293 | Chemie (HOH) |
Sequence modifications
A: 1 - 360 (UniProt: Q16539)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ser 162 | Cys 162 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43028.2 | |
| All* | Total formula weight | 43028.2 |
