1OZ1
P38 MITOGEN-ACTIVATED KINASE IN COMPLEX WITH 4-AZAINDOLE INHIBITOR
Summary for 1OZ1
Entry DOI | 10.2210/pdb1oz1/pdb |
Descriptor | Mitogen-activated protein kinase 14, 3-(4-FLUOROPHENYL)-2-PYRIDIN-4-YL-1H-PYRROLO[3,2-B]PYRIDIN-1-OL (3 entities in total) |
Functional Keywords | ser/thr protein kinase, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (By similarity): Q16539 |
Total number of polymer chains | 1 |
Total formula weight | 43054.02 |
Authors | Lovejoy, B.,Villasenor, A.,Browner, M.,Dunten, P. (deposition date: 2003-04-07, release date: 2003-09-23, Last modification date: 2024-02-14) |
Primary citation | Trejo, A.,Arzeno, H.,Browner, M.,Chanda, S.,Cheng, S.,Comer, D.D.,Dalrymple, S.A.,Dunten, P.,Lafargue, J.,Lovejoy, B.,Freire-Moar, J.,Lim, J.,Mcintosh, J.,Miller, J.,Papp, E.,Reuter, D.,Roberts, R.,Sanpablo, F.,Saunders, J.,Song, K.,Villasenor, A.,Warren, S.D.,Welch, M.,Weller, P.,Whiteley, P.E.,Zeng, L.,Goldstein, D.M. Design and synthesis of 4-azaindoles as inhibitors of p38 MAP kinase. J.Med.Chem., 46:4702-4713, 2003 Cited by PubMed: 14561090DOI: 10.1021/jm0301787 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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