1A9U
THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB203580
Summary for 1A9U
Entry DOI | 10.2210/pdb1a9u/pdb |
Descriptor | MAP KINASE P38, 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE (3 entities in total) |
Functional Keywords | transferase, map kinase, serine/threonine-protein kinase, p38 |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : Q16539 |
Total number of polymer chains | 1 |
Total formula weight | 43760.79 |
Authors | Wang, Z.,Canagarajah, B.,Boehm, J.C.,Kassis, S.,Cobb, M.H.,Young, P.R.,Abdel-Meguid, S.,Adams, J.L.,Goldsmith, E.J. (deposition date: 1998-04-10, release date: 1999-04-20, Last modification date: 2024-04-03) |
Primary citation | Wang, Z.,Canagarajah, B.J.,Boehm, J.C.,Kassisa, S.,Cobb, M.H.,Young, P.R.,Abdel-Meguid, S.,Adams, J.L.,Goldsmith, E.J. Structural basis of inhibitor selectivity in MAP kinases. Structure, 6:1117-1128, 1998 Cited by PubMed: 9753691DOI: 10.1016/S0969-2126(98)00113-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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