1IAN
HUMAN P38 MAP KINASE INHIBITOR COMPLEX
Summary for 1IAN
Entry DOI | 10.2210/pdb1ian/pdb |
Descriptor | P38 MAP KINASE, 4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE (2 entities in total) |
Functional Keywords | protein ser/thr-kinase, serine/threonine-protein kinase, serine-threonine-protein kinase complex |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q16539 |
Total number of polymer chains | 1 |
Total formula weight | 43561.03 |
Authors | Tong, L. (deposition date: 1997-03-07, release date: 1998-05-06, Last modification date: 2024-04-03) |
Primary citation | Tong, L.,Pav, S.,White, D.M.,Rogers, S.,Crane, K.M.,Cywin, C.L.,Brown, M.L.,Pargellis, C.A. A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket. Nat.Struct.Biol., 4:311-316, 1997 Cited by PubMed: 9095200DOI: 10.1038/nsb0497-311 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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