1ZZL
Crystal structure of P38 with triazolopyridine
Summary for 1ZZL
Entry DOI | 10.2210/pdb1zzl/pdb |
Descriptor | Mitogen-activated protein kinase 14, 6-[4-(4-FLUOROPHENYL)-1,3-OXAZOL-5-YL]-3-ISOPROPYL[1,2,4]TRIAZOLO[4,3-A]PYRIDINE (3 entities in total) |
Functional Keywords | phosphorylation, serine/threonine-protein kinase, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (By similarity): Q16539 |
Total number of polymer chains | 1 |
Total formula weight | 40585.38 |
Authors | McClure, K.F.,Han, S. (deposition date: 2005-06-14, release date: 2005-09-13, Last modification date: 2024-02-14) |
Primary citation | McClure, K.F.,Abramov, Y.A.,Laird, E.R.,Barberia, J.T.,Cai, W.,Carty, T.J.,Cortina, S.R.,Danley, D.E.,Dipesa, A.J.,Donahue, K.M.,Dombroski, M.A.,Elliott, N.C.,Gabel, C.A.,Han, S.,Hynes, T.R.,Lemotte, P.K.,Mansour, M.N.,Marr, E.S.,Letavic, M.A.,Pandit, J.,Ripin, D.B.,Sweeney, F.J.,Tan, D.,Tao, Y. Theoretical and Experimental Design of Atypical Kinase Inhibitors: Application to p38 MAP Kinase. J.Med.Chem., 48:5728-5737, 2005 Cited by PubMed: 16134941DOI: 10.1021/jm050346q PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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