Author results

5GAM
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FOOT REGION OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP
Descriptor:U5 snRNA, Pre-mRNA-splicing factor 8, Pre-mRNA-splicing factor SNU114, ...
Authors:Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K.
Deposit date:2015-12-15
Release date:2016-02-03
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Angstrom resolution
Nature, 530, 2016
3JBT
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ATOMIC STRUCTURE OF THE APAF-1 APOPTOSOME
Descriptor:Apoptotic protease-activating factor 1, Cytochrome c, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ...
Authors:Zhou, M., Li, Y., Hu, Q., Bai, X., Huang, W., Yan, C., Scheres, S.H.W., Shi, Y.
Deposit date:2015-10-15
Release date:2015-11-18
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1
Genes Dev., 29, 2015
4V5X
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THE CRYO-EM STRUCTURE OF A 3D DNA-ORIGAMI OBJECT
Descriptor:SCAFFOLD STRAND,SCAFFOLD STRAND, STAPLE STRAND
Authors:Bai, X.C., Martin, T.G., Scheres, S.H.W., Dietz, H.
Deposit date:2012-10-09
Release date:2014-07-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Cryo-Em Structure of a 3D DNA-Origami Object.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V8Y
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CRYO-EM RECONSTRUCTION OF THE 80S-EIF5B-MET-ITRNAMET EUKARYOTIC TRANSLATION INITIATION COMPLEX
Descriptor:40S RIBOSOMAL PROTEIN S26-A, 40S RIBOSOMAL PROTEIN S27-A, 40S RIBOSOMAL PROTEIN S28-A, ...
Authors:Fernandez, I.S., Bai, X.C., Hussain, T., Kelley, A.C., Lorsch, J.R., Ramakrishnan, V., Scheres, S.H.W.
Deposit date:2013-07-20
Release date:2014-07-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
4V8Z
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CRYO-EM RECONSTRUCTION OF THE 80S-EIF5B-MET-ITRNAMET EUKARYOTIC TRANSLATION INITIATION COMPLEX
Descriptor:40S RIBOSOMAL PROTEIN S26-A, 40S RIBOSOMAL PROTEIN S27-A, 40S RIBOSOMAL PROTEIN S28-A, ...
Authors:Fernandez, I.S., Bai, X.C., Hussain, T., Kelley, A.C., Lorsch, J.R., Ramakrishnan, V., Scheres, S.H.W.
Deposit date:2013-07-20
Release date:2014-07-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
4V91
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KLUYVEROMYCES LACTIS 80S RIBOSOME IN COMPLEX WITH CRPV-IRES
Descriptor:25S RRNA, 5S RRNA, 5.8S RRNA, ...
Authors:Fernandez, I.S., Bai, X., Scheres, S.H.W., Ramakrishnan, V.
Deposit date:2014-03-21
Release date:2014-07-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome.
Cell(Cambridge,Mass.), 157, 2014
4V92
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KLUYVEROMYCES LACTIS 80S RIBOSOME IN COMPLEX WITH CRPV-IRES
Descriptor:18S RRNA, RNA OF CRICKET-PARALYSIS-VIRUS-IRES, US2, ...
Authors:Fernandez, I.S., Bai, X., Scheres, S.H.W., Ramakrishnan, V.
Deposit date:2014-03-21
Release date:2014-07-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome.
Cell(Cambridge,Mass.), 157, 2014
5A63
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CRYO-EM STRUCTURE OF THE HUMAN GAMMA-SECRETASE COMPLEX AT 3.4 ANGSTROM RESOLUTION.
Descriptor:Nicastrin, Presenilin-1, Gamma-secretase subunit APH-1A, ...
Authors:Bai, X., Yan, C., Yang, G., Lu, P., Ma, D., Sun, L., Zhou, R., Scheres, S.H.W., Shi, Y.
Deposit date:2015-06-24
Release date:2015-08-05
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:An Atomic Structure of Human Gamma-Secretase
Nature, 525, 2015
5N9Y
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THE FULL-LENGTH STRUCTURE OF ZNTB
Descriptor:Zinc transport protein ZntB
Authors:Cornelius, G., Stetsenko, A., Scheres, S.H.W., Slotboom, D.J., Guskov, A.
Deposit date:2017-02-27
Release date:2017-11-15
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The structural basis of proton driven zinc transport by ZntB.
Nat Commun, 8, 2017
5NIK
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STRUCTURE OF THE MACAB-TOLC ABC-TYPE TRIPARTITE MULTIDRUG EFFLUX PUMP
Descriptor:Outer membrane protein TolC, Macrolide export protein MacA, Macrolide export ATP-binding/permease protein MacB
Authors:Fitzpatrick, A.W.P., Llabres, S., Neuberger, A., Blaza, J.N., Bai, X.-C., Okada, U., Murakami, S., van Veen, H.W., Zachariae, U., Scheres, S.H.W., Luisi, B.F., Du, D.
Deposit date:2017-03-24
Release date:2017-05-24
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump.
Nat Microbiol, 2, 2017
5NIL
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STRUCTURE OF THE MACAB-TOLC ABC-TYPE TRIPARTITE MULTIDRUG EFFLUX PUMP-MACB SECTION
Descriptor:Outer membrane protein TolC, Macrolide export protein MacA, Macrolide export ATP-binding/permease protein MacB
Authors:Fitzpatrick, A.W.P., Llabres, S., Neuberger, A., Blaza, J.N., Bai, X.-C., Okada, U., Murakami, S., van Veen, H.W., Zachariae, U., Scheres, S.H.W., Luisi, B.F., Du, D.
Deposit date:2017-03-24
Release date:2017-05-24
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump.
Nat Microbiol, 2, 2017
5O3L
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PAIRED HELICAL FILAMENT IN ALZHEIMER'S DISEASE BRAIN
Descriptor:Microtubule-associated protein tau
Authors:Fitzpatrick, A.W.P., Falcon, B., He, S., Murzin, A.G., Murshudov, G., Garringer, H.G., Crowther, R.A., Ghetti, B., Goedert, M., Scheres, S.H.W.
Deposit date:2017-05-24
Release date:2017-07-26
Last modified:2019-07-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5O3O
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PRONASE-TREATED PAIRED HELICAL FILAMENT IN ALZHEIMER'S DISEASE BRAIN
Descriptor:Microtubule-associated protein tau
Authors:Fitzpatrick, A.W.P., Falcon, B., He, S., Murzin, A.G., Murshudov, G., Garringer, H.G., Crowther, R.A., Ghetti, B., Goedert, M., Scheres, S.H.W.
Deposit date:2017-05-24
Release date:2017-07-26
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5O3T
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STRAIGHT FILAMENT IN ALZHEIMER'S DISEASE BRAIN
Descriptor:Microtubule-associated protein tau
Authors:Fitzpatrick, A.W.P., Falcon, B., He, S., Murzin, A.G., Murshudov, G., Garringer, H.G., Crowther, R.A., Ghetti, B., Goedert, M., Scheres, S.H.W.
Deposit date:2017-05-24
Release date:2017-07-26
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
6GX5
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NARROW PICK FILAMENT FROM PICK'S DISEASE BRAIN
Descriptor:Microtubule-associated protein tau
Authors:Falcon, B., Zhang, W., Murzin, A.G., Murshudov, G., Garringer, H.J., Vidal, R., Crowther, R.A., Ghetti, B., Scheres, S.H.W., Goedert, M.
Deposit date:2018-06-26
Release date:2018-09-12
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of filaments from Pick's disease reveal a novel tau protein fold.
Nature, 561, 2018
6HRE
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PAIRED HELICAL FILAMENT FROM SPORADIC ALZHEIMER'S DISEASE BRAIN
Descriptor:Microtubule-associated protein tau
Authors:Falcon, B., Zhang, W., Schweighauser, M., Murzin, A.G., Vidal, R., Garringer, H.J., Ghetti, B., Scheres, S.H.W., Goedert, M.
Deposit date:2018-09-26
Release date:2018-10-10
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
6HRF
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STRAIGHT FILAMENT FROM SPORADIC ALZHEIMER'S DISEASE BRAIN
Descriptor:Microtubule-associated protein tau
Authors:Falcon, B., Zhang, W., Schweighauser, M., Murzin, A.G., Vidal, R., Garringer, H.J., Ghetti, B., Scheres, S.H.W., Goedert, M.
Deposit date:2018-09-26
Release date:2018-10-10
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
6SRI
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STRUCTURE OF THE FANCONI ANAEMIA CORE COMPLEX
Descriptor:Unassigned secondary structure elements (central region, proposed FANCB-FAAP100: chain A,a; base region, proposed FANCC-FANC-E-FANCF: chain 3), ...
Authors:Shakeel, S., Rajendra, E., Alcon, P., He, S., Scheres, S.H.W., Passmore, L.A.
Deposit date:2019-09-05
Release date:2019-11-06
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
6SRS
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STRUCTURE OF THE FANCONI ANAEMIA CORE SUBCOMPLEX
Descriptor:Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), Unassigned secondary structure elements (proposed FANCB), ...
Authors:Shakeel, S., Rajendra, E., Alcon, P., He, S., Scheres, S.H.W., Passmore, L.A.
Deposit date:2019-09-05
Release date:2019-11-06
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
6TJO
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CRYO-EM STRUCTURE OF TYPEI TAU FILAMENTS EXTRACTED FROM THE BRAINS OF INDIVIDUALS WITH CORTICOBASAL DEGENERATION
Descriptor:Microtubule-associated protein tau
Authors:Zhang, W., Murzin, A.G., Falcon, B., Shi, Y., Goedert, M., Scheres, S.H.W.
Deposit date:2019-11-26
Release date:2020-02-05
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
6TJX
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CRYO-EM STRUCTURE OF TYPEII TAU FILAMENTS EXTRACTED FROM THE BRAINS OF INDIVIDUALS WITH CORTICOBASAL DEGENERATION
Descriptor:Microtubule-associated protein tau
Authors:Zhang, W., Murzin, A.G., Falcon, B., Shi, Y., Goedert, M., Scheres, S.H.W.
Deposit date:2019-11-27
Release date:2020-02-05
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
6VPS
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CRYO-EM STRUCTURE OF THE AMYLOID CORE OF DROSOPHILA ORB2 ISOLATED FROM HEAD
Descriptor:Translational regulator orb2
Authors:Hervas, R., Rau, M.J., Park, Y., Zhang, W., Murzin, A.G., Fitzpatrick, J.A.J., Scheres, S.H.W., Si, K.
Deposit date:2020-02-04
Release date:2020-03-18
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila
Science, 367, 2020
6XYO
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MULTIPLE SYSTEM ATROPHY TYPE I ALPHA-SYNUCLEIN FILAMENT
Descriptor:Alpha-synuclein
Authors:Schweighauser, M., Shi, Y., Tarutani, A., Kametani, F., Murzin, A.G., Ghetti, B., Matsubara, T., Tomita, T., Ando, T., Hasegawa, K., Murayama, S., Yoshida, M., Hasegawa, M., Scheres, S.H.W., Goedert, M.
Deposit date:2020-01-30
Release date:2020-02-12
Last modified:2020-06-10
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 2020
6XYP
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MULTIPLE SYSTEM ATROPHY TYPE II-1 ALPHA-SYNUCLEIN FILAMENT
Descriptor:Alpha-synuclein
Authors:Schweighauser, M., Shi, Y., Tarutani, A., Kametani, F., Murzin, A.G., Ghetti, B., Matsubara, T., Tomita, T., Ando, T., Hasegawa, K., Murayama, S., Yoshida, M., Hasegawa, M., Scheres, S.H.W., Goedert, M.
Deposit date:2020-01-30
Release date:2020-02-12
Last modified:2020-06-10
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 2020
6XYQ
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MULTIPLE SYSTEM ATROPHY TYPE II-2 ALPHA-SYNUCLEIN FILAMENT
Descriptor:Alpha-synuclein
Authors:Schweighauser, M., Shi, Y., Tarutani, A., Kametani, F., Murzin, A.G., Ghetti, B., Matsubara, T., Tomita, T., Ando, T., Hasegawa, K., Murayama, S., Yoshida, M., Hasegawa, M., Scheres, S.H.W., Goedert, M.
Deposit date:2020-01-30
Release date:2020-02-12
Last modified:2020-06-10
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 2020
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167327
PDB entries from 2020-08-05