5GAM | | FOOT REGION OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP | | Descriptor: | U5 snRNA, Pre-mRNA-splicing factor 8, Pre-mRNA-splicing factor SNU114, ... | | Authors: | Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K. | | Deposit date: | 2015-12-15 | | Release date: | 2016-02-03 | | Last modified: | 2019-10-02 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Angstrom resolution
Nature, 530, 2016
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3JBT | | ATOMIC STRUCTURE OF THE APAF-1 APOPTOSOME | | Descriptor: | Apoptotic protease-activating factor 1, Cytochrome c, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ... | | Authors: | Zhou, M., Li, Y., Hu, Q., Bai, X., Huang, W., Yan, C., Scheres, S.H.W., Shi, Y. | | Deposit date: | 2015-10-15 | | Release date: | 2015-11-18 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1
Genes Dev., 29, 2015
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4V5X | | THE CRYO-EM STRUCTURE OF A 3D DNA-ORIGAMI OBJECT | | Descriptor: | SCAFFOLD STRAND,SCAFFOLD STRAND, STAPLE STRAND | | Authors: | Bai, X.C., Martin, T.G., Scheres, S.H.W., Dietz, H. | | Deposit date: | 2012-10-09 | | Release date: | 2014-07-09 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (11.5 Å) | | Cite: | Cryo-Em Structure of a 3D DNA-Origami Object.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4V8Y | | CRYO-EM RECONSTRUCTION OF THE 80S-EIF5B-MET-ITRNAMET EUKARYOTIC TRANSLATION INITIATION COMPLEX | | Descriptor: | 40S RIBOSOMAL PROTEIN S26-A, 40S RIBOSOMAL PROTEIN S27-A, 40S RIBOSOMAL PROTEIN S28-A, ... | | Authors: | Fernandez, I.S., Bai, X.C., Hussain, T., Kelley, A.C., Lorsch, J.R., Ramakrishnan, V., Scheres, S.H.W. | | Deposit date: | 2013-07-20 | | Release date: | 2014-07-09 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
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4V8Z | | CRYO-EM RECONSTRUCTION OF THE 80S-EIF5B-MET-ITRNAMET EUKARYOTIC TRANSLATION INITIATION COMPLEX | | Descriptor: | 40S RIBOSOMAL PROTEIN S26-A, 40S RIBOSOMAL PROTEIN S27-A, 40S RIBOSOMAL PROTEIN S28-A, ... | | Authors: | Fernandez, I.S., Bai, X.C., Hussain, T., Kelley, A.C., Lorsch, J.R., Ramakrishnan, V., Scheres, S.H.W. | | Deposit date: | 2013-07-20 | | Release date: | 2014-07-09 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
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4V91 | | KLUYVEROMYCES LACTIS 80S RIBOSOME IN COMPLEX WITH CRPV-IRES | | Descriptor: | 25S RRNA, 5S RRNA, 5.8S RRNA, ... | | Authors: | Fernandez, I.S., Bai, X., Scheres, S.H.W., Ramakrishnan, V. | | Deposit date: | 2014-03-21 | | Release date: | 2014-07-09 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome.
Cell(Cambridge,Mass.), 157, 2014
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4V92 | | KLUYVEROMYCES LACTIS 80S RIBOSOME IN COMPLEX WITH CRPV-IRES | | Descriptor: | 18S RRNA, RNA OF CRICKET-PARALYSIS-VIRUS-IRES, US2, ... | | Authors: | Fernandez, I.S., Bai, X., Scheres, S.H.W., Ramakrishnan, V. | | Deposit date: | 2014-03-21 | | Release date: | 2014-07-09 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome.
Cell(Cambridge,Mass.), 157, 2014
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5A63 | | CRYO-EM STRUCTURE OF THE HUMAN GAMMA-SECRETASE COMPLEX AT 3.4 ANGSTROM RESOLUTION. | | Descriptor: | Nicastrin, Presenilin-1, Gamma-secretase subunit APH-1A, ... | | Authors: | Bai, X., Yan, C., Yang, G., Lu, P., Ma, D., Sun, L., Zhou, R., Scheres, S.H.W., Shi, Y. | | Deposit date: | 2015-06-24 | | Release date: | 2015-08-05 | | Last modified: | 2019-09-11 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | An Atomic Structure of Human Gamma-Secretase
Nature, 525, 2015
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5N9Y | | THE FULL-LENGTH STRUCTURE OF ZNTB | | Descriptor: | Zinc transport protein ZntB | | Authors: | Cornelius, G., Stetsenko, A., Scheres, S.H.W., Slotboom, D.J., Guskov, A. | | Deposit date: | 2017-02-27 | | Release date: | 2017-11-15 | | Last modified: | 2019-10-23 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | The structural basis of proton driven zinc transport by ZntB.
Nat Commun, 8, 2017
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5NIK | | STRUCTURE OF THE MACAB-TOLC ABC-TYPE TRIPARTITE MULTIDRUG EFFLUX PUMP | | Descriptor: | Outer membrane protein TolC, Macrolide export protein MacA, Macrolide export ATP-binding/permease protein MacB | | Authors: | Fitzpatrick, A.W.P., Llabres, S., Neuberger, A., Blaza, J.N., Bai, X.-C., Okada, U., Murakami, S., van Veen, H.W., Zachariae, U., Scheres, S.H.W., Luisi, B.F., Du, D. | | Deposit date: | 2017-03-24 | | Release date: | 2017-05-24 | | Last modified: | 2019-10-23 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump.
Nat Microbiol, 2, 2017
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5NIL | | STRUCTURE OF THE MACAB-TOLC ABC-TYPE TRIPARTITE MULTIDRUG EFFLUX PUMP-MACB SECTION | | Descriptor: | Outer membrane protein TolC, Macrolide export protein MacA, Macrolide export ATP-binding/permease protein MacB | | Authors: | Fitzpatrick, A.W.P., Llabres, S., Neuberger, A., Blaza, J.N., Bai, X.-C., Okada, U., Murakami, S., van Veen, H.W., Zachariae, U., Scheres, S.H.W., Luisi, B.F., Du, D. | | Deposit date: | 2017-03-24 | | Release date: | 2017-05-24 | | Last modified: | 2019-10-23 | | Method: | ELECTRON MICROSCOPY (5.3 Å) | | Cite: | Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump.
Nat Microbiol, 2, 2017
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5O3L | | PAIRED HELICAL FILAMENT IN ALZHEIMER'S DISEASE BRAIN | | Descriptor: | Microtubule-associated protein tau | | Authors: | Fitzpatrick, A.W.P., Falcon, B., He, S., Murzin, A.G., Murshudov, G., Garringer, H.G., Crowther, R.A., Ghetti, B., Goedert, M., Scheres, S.H.W. | | Deposit date: | 2017-05-24 | | Release date: | 2017-07-26 | | Last modified: | 2019-07-24 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
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5O3O | | PRONASE-TREATED PAIRED HELICAL FILAMENT IN ALZHEIMER'S DISEASE BRAIN | | Descriptor: | Microtubule-associated protein tau | | Authors: | Fitzpatrick, A.W.P., Falcon, B., He, S., Murzin, A.G., Murshudov, G., Garringer, H.G., Crowther, R.A., Ghetti, B., Goedert, M., Scheres, S.H.W. | | Deposit date: | 2017-05-24 | | Release date: | 2017-07-26 | | Last modified: | 2017-08-02 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
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5O3T | | STRAIGHT FILAMENT IN ALZHEIMER'S DISEASE BRAIN | | Descriptor: | Microtubule-associated protein tau | | Authors: | Fitzpatrick, A.W.P., Falcon, B., He, S., Murzin, A.G., Murshudov, G., Garringer, H.G., Crowther, R.A., Ghetti, B., Goedert, M., Scheres, S.H.W. | | Deposit date: | 2017-05-24 | | Release date: | 2017-07-26 | | Last modified: | 2017-08-02 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
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6GX5 | | NARROW PICK FILAMENT FROM PICK'S DISEASE BRAIN | | Descriptor: | Microtubule-associated protein tau | | Authors: | Falcon, B., Zhang, W., Murzin, A.G., Murshudov, G., Garringer, H.J., Vidal, R., Crowther, R.A., Ghetti, B., Scheres, S.H.W., Goedert, M. | | Deposit date: | 2018-06-26 | | Release date: | 2018-09-12 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structures of filaments from Pick's disease reveal a novel tau protein fold.
Nature, 561, 2018
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6HRE | | PAIRED HELICAL FILAMENT FROM SPORADIC ALZHEIMER'S DISEASE BRAIN | | Descriptor: | Microtubule-associated protein tau | | Authors: | Falcon, B., Zhang, W., Schweighauser, M., Murzin, A.G., Vidal, R., Garringer, H.J., Ghetti, B., Scheres, S.H.W., Goedert, M. | | Deposit date: | 2018-09-26 | | Release date: | 2018-10-10 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
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6HRF | | STRAIGHT FILAMENT FROM SPORADIC ALZHEIMER'S DISEASE BRAIN | | Descriptor: | Microtubule-associated protein tau | | Authors: | Falcon, B., Zhang, W., Schweighauser, M., Murzin, A.G., Vidal, R., Garringer, H.J., Ghetti, B., Scheres, S.H.W., Goedert, M. | | Deposit date: | 2018-09-26 | | Release date: | 2018-10-10 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
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6SRI | | STRUCTURE OF THE FANCONI ANAEMIA CORE COMPLEX | | Descriptor: | Unassigned secondary structure elements (central region, proposed FANCB-FAAP100: chain A,a; base region, proposed FANCC-FANC-E-FANCF: chain 3), ... | | Authors: | Shakeel, S., Rajendra, E., Alcon, P., He, S., Scheres, S.H.W., Passmore, L.A. | | Deposit date: | 2019-09-05 | | Release date: | 2019-11-06 | | Last modified: | 2019-11-20 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
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6SRS | | STRUCTURE OF THE FANCONI ANAEMIA CORE SUBCOMPLEX | | Descriptor: | Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), Unassigned secondary structure elements (proposed FANCB), ... | | Authors: | Shakeel, S., Rajendra, E., Alcon, P., He, S., Scheres, S.H.W., Passmore, L.A. | | Deposit date: | 2019-09-05 | | Release date: | 2019-11-06 | | Last modified: | 2019-11-20 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
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6TJO | | CRYO-EM STRUCTURE OF TYPEI TAU FILAMENTS EXTRACTED FROM THE BRAINS OF INDIVIDUALS WITH CORTICOBASAL DEGENERATION | | Descriptor: | Microtubule-associated protein tau | | Authors: | Zhang, W., Murzin, A.G., Falcon, B., Shi, Y., Goedert, M., Scheres, S.H.W. | | Deposit date: | 2019-11-26 | | Release date: | 2020-02-05 | | Last modified: | 2020-02-26 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Novel tau filament fold in corticobasal degeneration.
Nature, 2020
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6TJX | | CRYO-EM STRUCTURE OF TYPEII TAU FILAMENTS EXTRACTED FROM THE BRAINS OF INDIVIDUALS WITH CORTICOBASAL DEGENERATION | | Descriptor: | Microtubule-associated protein tau | | Authors: | Zhang, W., Murzin, A.G., Falcon, B., Shi, Y., Goedert, M., Scheres, S.H.W. | | Deposit date: | 2019-11-27 | | Release date: | 2020-02-05 | | Last modified: | 2020-02-26 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Novel tau filament fold in corticobasal degeneration.
Nature, 2020
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6XYO | | MULTIPLE SYSTEM ATROPHY TYPE I ALPHA-SYNUCLEIN FILAMENT | | Descriptor: | Alpha-synuclein | | Authors: | Schweighauser, M., Shi, Y., Tarutani, A., Kametani, F., Murzin, A.G., Ghetti, B., Matsubara, T., Tomita, T., Ando, T., Hasegawa, K., Murayama, S., Yoshida, M., Hasegawa, M., Scheres, S.H.W., Goedert, M. | | Deposit date: | 2020-01-30 | | Release date: | 2020-02-12 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structures of alpha-synuclein filaments from multiple system atrophy.
To Be Published
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6XYP | | MULTIPLE SYSTEM ATROPHY TYPE II-1 ALPHA-SYNUCLEIN FILAMENT | | Descriptor: | Alpha-synuclein | | Authors: | Schweighauser, M., Shi, Y., Tarutani, A., Kametani, F., Murzin, A.G., Ghetti, B., Matsubara, T., Tomita, T., Ando, T., Hasegawa, K., Murayama, S., Yoshida, M., Hasegawa, M., Scheres, S.H.W., Goedert, M. | | Deposit date: | 2020-01-30 | | Release date: | 2020-02-12 | | Method: | ELECTRON MICROSCOPY (3.29 Å) | | Cite: | Structures of alpha-synuclein filaments from multiple system atrophy.
To Be Published
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6XYQ | | MULTIPLE SYSTEM ATROPHY TYPE II-2 ALPHA-SYNUCLEIN FILAMENT | | Descriptor: | Alpha-synuclein | | Authors: | Schweighauser, M., Shi, Y., Tarutani, A., Kametani, F., Murzin, A.G., Ghetti, B., Matsubara, T., Tomita, T., Ando, T., Hasegawa, K., Murayama, S., Yoshida, M., Hasegawa, M., Scheres, S.H.W., Goedert, M. | | Deposit date: | 2020-01-30 | | Release date: | 2020-02-12 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Structures of alpha-synuclein filaments from multiple system atrophy.
To Be Published
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5GAN | | THE OVERALL STRUCTURE OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP AT 3.7 ANGSTROM | | Descriptor: | U4 snRNA, U6 snRNA, Pre-mRNA-splicing factor 8, ... | | Authors: | Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K. | | Deposit date: | 2015-12-15 | | Release date: | 2016-01-27 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
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