6XYP
Multiple system atrophy Type II-1 alpha-synuclein filament
Summary for 6XYP
Entry DOI | 10.2210/pdb6xyp/pdb |
EMDB information | 10651 |
Descriptor | Alpha-synuclein (1 entity in total) |
Functional Keywords | multiple system atrophy, alpha-synuclein filament, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 10 |
Total formula weight | 144761.08 |
Authors | Schweighauser, M.,Shi, Y.,Tarutani, A.,Kametani, F.,Murzin, A.G.,Ghetti, B.,Matsubara, T.,Tomita, T.,Ando, T.,Hasegawa, K.,Murayama, S.,Yoshida, M.,Hasegawa, M.,Scheres, S.H.W.,Goedert, M. (deposition date: 2020-01-30, release date: 2020-02-12, Last modification date: 2024-05-22) |
Primary citation | Schweighauser, M.,Shi, Y.,Tarutani, A.,Kametani, F.,Murzin, A.G.,Ghetti, B.,Matsubara, T.,Tomita, T.,Ando, T.,Hasegawa, K.,Murayama, S.,Yoshida, M.,Hasegawa, M.,Scheres, S.H.W.,Goedert, M. Structures of alpha-synuclein filaments from multiple system atrophy. Nature, 585:464-469, 2020 Cited by PubMed: 32461689DOI: 10.1038/s41586-020-2317-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.29 Å) |
Structure validation
Download full validation report