6TJX
Cryo-EM structure of TypeII tau filaments extracted from the brains of individuals with Corticobasal degeneration
Summary for 6TJX
| Entry DOI | 10.2210/pdb6tjx/pdb |
| EMDB information | 10512 10514 |
| Descriptor | Microtubule-associated protein tau (1 entity in total) |
| Functional Keywords | tau protein, filament, cross-beta structure, protein fibril |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 6 |
| Total formula weight | 275519.23 |
| Authors | Zhang, W.,Murzin, A.G.,Falcon, B.,Shi, Y.,Goedert, M.,Scheres, S.H.W. (deposition date: 2019-11-27, release date: 2020-02-05, Last modification date: 2020-04-22) |
| Primary citation | Zhang, W.,Tarutani, A.,Newell, K.L.,Murzin, A.G.,Matsubara, T.,Falcon, B.,Vidal, R.,Garringer, H.J.,Shi, Y.,Ikeuchi, T.,Murayama, S.,Ghetti, B.,Hasegawa, M.,Goedert, M.,Scheres, S.H.W. Novel tau filament fold in corticobasal degeneration. Nature, 580:283-287, 2020 Cited by PubMed: 32050258DOI: 10.1038/s41586-020-2043-0 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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