9EOH
PHF type tau filament from in vitro V337M mutant
Summary for 9EOH
Entry DOI | 10.2210/pdb9eoh/pdb |
Related | 9EO7 |
EMDB information | 19855 |
Descriptor | Isoform Tau-F of Microtubule-associated protein tau (1 entity in total) |
Functional Keywords | phf, tau filament, v337m, protein fibril |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 6 |
Total formula weight | 275711.63 |
Authors | Qi, C.,Lovestam, S.,Scheres, S.H.W.,Michel, G. (deposition date: 2024-03-14, release date: 2024-05-29) |
Primary citation | Qi, C.,Lovestam, S.,Murzin, A.G.,Peak-Chew, S.,Franco, C.,Bogdani, M.,Latimer, C.,Murrell, J.R.,Cullinane, P.W.,Jaunmuktane, Z.,Bird, T.D.,Ghetti, B.,Scheres, S.H.W.,Goedert, M. Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W. Biorxiv, 2024 Cited by PubMed: 38746388DOI: 10.1101/2024.04.29.591661 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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