6VPS

Cryo-EM structure of the amyloid core of Drosophila Orb2 isolated from head

Summary for 6VPS

Entry DOI	10.2210/pdb6vps/pdb
EMDB information	21316
Descriptor	Translational regulator orb2 (1 entity in total)
Functional Keywords	amyloid, prion-like, long-term memory, protein fibril
Biological source	Drosophila melanogaster (Fruit fly)
Total number of polymer chains	9
Total formula weight	35767.53
Authors	Hervas, R.,Rau, M.J.,Park, Y.,Zhang, W.,Murzin, A.G.,Fitzpatrick, J.A.J.,Scheres, S.H.W.,Si, K. (deposition date: 2020-02-04, release date: 2020-03-18, Last modification date: 2024-03-06)
Primary citation	Hervas, R.,Rau, M.J.,Park, Y.,Zhang, W.,Murzin, A.G.,Fitzpatrick, J.A.J.,Scheres, S.H.W.,Si, K. Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila Science, 367:1230-1234, 2020 Cited by DOI: 10.1126/science.aba3526 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.6 Å)

Structure validation