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PDB: 158 results

4V5X
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BU of 4v5x by Molmil
The cryo-EM structure of a 3D DNA-origami object
Descriptor: SCAFFOLD STRAND,SCAFFOLD STRAND, STAPLE STRAND
Authors:Bai, X.C, Martin, T.G, Scheres, S.H.W, Dietz, H.
Deposit date:2012-10-09
Release date:2014-07-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Cryo-Em Structure of a 3D DNA-Origami Object.
Proc.Natl.Acad.Sci.USA, 109, 2012
6XPD
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BU of 6xpd by Molmil
Cryo-EM structure of human ZnT8 double mutant - D110N and D224N, determined in outward-facing conformation
Descriptor: ZINC ION, Zinc transporter 8
Authors:Bai, X.C, Xue, J, Jiang, Y.X.
Deposit date:2020-07-08
Release date:2020-08-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations.
Elife, 9, 2020
6XPF
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BU of 6xpf by Molmil
Cryo-EM structure of human ZnT8 WT, in the absence of zinc, determined in heterogeneous conformations- one subunit in an inward-facing and the other in an outward-facing conformation
Descriptor: ZINC ION, Zinc transporter 8
Authors:Bai, X.C, Xue, J, Jiang, Y.X.
Deposit date:2020-07-08
Release date:2020-08-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations.
Elife, 9, 2020
4Q2W
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BU of 4q2w by Molmil
Crystal Structure of pneumococcal peptidoglycan hydrolase LytB
Descriptor: GLYCEROL, Putative endo-beta-N-acetylglucosaminidase
Authors:Bai, X.H, Chen, H.J, Jiang, Y.L, Wen, Z, Cheng, W, Li, Q, Zhang, J.R, Chen, Y, Zhou, C.Z.
Deposit date:2014-04-10
Release date:2014-07-16
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of pneumococcal peptidoglycan hydrolase LytB reveals insights into the bacterial cell wall remodeling and pathogenesis.
J.Biol.Chem., 289, 2014
5A63
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BU of 5a63 by Molmil
Cryo-EM structure of the human gamma-secretase complex at 3.4 angstrom resolution.
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Bai, X, Yan, C, Yang, G, Lu, P, Ma, D, Sun, L, Zhou, R, Scheres, S.H.W, Shi, Y.
Deposit date:2015-06-24
Release date:2015-08-05
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:An Atomic Structure of Human Gamma-Secretase
Nature, 525, 2015
6XPE
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BU of 6xpe by Molmil
Cryo-EM structure of human ZnT8 WT, in the presence of zinc, determined in outward-facing conformation
Descriptor: ZINC ION, Zinc transporter 8
Authors:Bai, X.C, Xue, J, Jiang, Y.X.
Deposit date:2020-07-08
Release date:2020-08-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations.
Elife, 9, 2020
7SL7
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BU of 7sl7 by Molmil
Full-length insulin receptor bound with both site 1 binding deficient mutant insulin (A-V3E) and site 2 binding deficient mutant insulin (A-L13R)
Descriptor: Insulin A chain (L13R), Insulin A chain (V3E), Insulin B chain, ...
Authors:Bai, X.C, Choi, E.
Deposit date:2021-10-22
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STJ
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BU of 7stj by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 1)
Descriptor: Insulin, Insulin receptor
Authors:Bai, X.C, Choi, E.
Deposit date:2021-11-14
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL4
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BU of 7sl4 by Molmil
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- asymmetric conformation
Descriptor: Insulin A chain, Insulin B chain, Insulin receptor
Authors:Bai, X.C, Choi, E.
Deposit date:2021-10-22
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL3
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BU of 7sl3 by Molmil
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- symmetric conformation
Descriptor: Insulin A chain, Insulin B chain, Insulin receptor
Authors:Bai, X.C, Choi, E.
Deposit date:2021-10-22
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL1
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BU of 7sl1 by Molmil
Full-length insulin receptor bound with site 1 binding deficient mutant insulin (A-V3E)
Descriptor: Insulin A chain, Insulin B chain, Insulin receptor
Authors:Bai, X.C, Choi, E.
Deposit date:2021-10-22
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL2
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BU of 7sl2 by Molmil
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- asymmetric conformation
Descriptor: Insulin A chain, Insulin B chain, Insulin receptor
Authors:Bai, X.C, Choi, E.
Deposit date:2021-10-22
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STK
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BU of 7stk by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 2)
Descriptor: Insulin, Insulin receptor
Authors:Bai, X.C, Choi, E.
Deposit date:2021-11-14
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL6
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BU of 7sl6 by Molmil
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- symmetric conformation
Descriptor: Insulin A chain, Insulin B chain, Insulin receptor
Authors:Bai, X.C, Choi, E.
Deposit date:2021-10-22
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STI
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BU of 7sti by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (1 insulin bound) asymmetric conformation
Descriptor: Insulin, Insulin receptor
Authors:Bai, X.C, Choi, E.
Deposit date:2021-11-13
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STH
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BU of 7sth by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (2 insulin bound) symmetric conformation
Descriptor: Insulin, Insulin receptor
Authors:Bai, X.C, Choi, E.
Deposit date:2021-11-13
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
3Q0K
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BU of 3q0k by Molmil
Crystal structure of Human PACSIN 2 F-BAR
Descriptor: CALCIUM ION, Protein kinase C and casein kinase substrate in neurons protein 2
Authors:Bai, X, Meng, G, Zheng, X.
Deposit date:2010-12-15
Release date:2012-02-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human PACSIN 2 F-BAR domain
To be Published
5FN3
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BU of 5fn3 by Molmil
Cryo-EM structure of gamma secretase in class 1 of the apo- state ensemble
Descriptor: Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ...
Authors:Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2019-09-11
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN2
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BU of 5fn2 by Molmil
Cryo-EM structure of gamma secretase in complex with a drug DAPT
Descriptor: Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ...
Authors:Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2019-09-04
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN4
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BU of 5fn4 by Molmil
Cryo-EM structure of gamma secretase in class 2 of the apo- state ensemble
Descriptor: Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ...
Authors:Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2019-09-11
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN5
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BU of 5fn5 by Molmil
Cryo-EM structure of gamma secretase in class 3 of the apo- state ensemble
Descriptor: Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ...
Authors:Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2019-09-11
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
3Q84
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BU of 3q84 by Molmil
Crystal structure of human PACSIN 1 F-BAR domain
Descriptor: CALCIUM ION, Protein kinase C and casein kinase substrate in neurons protein 1
Authors:Bai, X.
Deposit date:2011-01-06
Release date:2012-02-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human PACSIN 1 F-BAR domain
To be Published
5GL0
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BU of 5gl0 by Molmil
Structure of RyR1 in a closed state (C4 conformer)
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ZINC ION
Authors:Bai, X.C, Yan, Z, Wu, J.P, Yan, N.
Deposit date:2016-07-07
Release date:2016-08-24
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
5GKZ
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BU of 5gkz by Molmil
Structure of RyR1 in a closed state (C3 conformer)
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ZINC ION
Authors:Bai, X.C, Yan, Z, Wu, J.P, Yan, N.
Deposit date:2016-07-07
Release date:2016-08-24
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
5GL1
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BU of 5gl1 by Molmil
Structure of RyR1 in an open state
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ZINC ION
Authors:Bai, X.C, Yan, Z, Wu, J.P, Yan, N.
Deposit date:2016-07-07
Release date:2016-08-24
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016

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