6XYO

Multiple system atrophy Type I alpha-synuclein filament

Summary for 6XYO

Entry DOI	10.2210/pdb6xyo/pdb
EMDB information	10650
Descriptor	Alpha-synuclein (1 entity in total)
Functional Keywords	multiple system atrophy, alpha-synuclein filament, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	10
Total formula weight	144761.08
Authors	Schweighauser, M.,Shi, Y.,Tarutani, A.,Kametani, F.,Murzin, A.G.,Ghetti, B.,Matsubara, T.,Tomita, T.,Ando, T.,Hasegawa, K.,Murayama, S.,Yoshida, M.,Hasegawa, M.,Scheres, S.H.W.,Goedert, M. (deposition date: 2020-01-30, release date: 2020-02-12, Last modification date: 2020-09-30)
Primary citation	Schweighauser, M.,Shi, Y.,Tarutani, A.,Kametani, F.,Murzin, A.G.,Ghetti, B.,Matsubara, T.,Tomita, T.,Ando, T.,Hasegawa, K.,Murayama, S.,Yoshida, M.,Hasegawa, M.,Scheres, S.H.W.,Goedert, M. Structures of alpha-synuclein filaments from multiple system atrophy. Nature, 585:464-469, 2020 Cited by PubMed: 32461689 DOI: 10.1038/s41586-020-2317-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.6 Å)

Structure validation