6HRF
Straight filament from sporadic Alzheimer's disease brain
Summary for 6HRF
Entry DOI | 10.2210/pdb6hrf/pdb |
Related | 5O3T 6HRE |
EMDB information | 0259 0260 3743 |
Descriptor | Microtubule-associated protein tau (1 entity in total) |
Functional Keywords | tau, helical, filament, fibril, amyloid, alzheimer's disease, sf, straight filament, nft, neurofibrillary tangly, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 6 |
Total formula weight | 275519.23 |
Authors | Falcon, B.,Zhang, W.,Schweighauser, M.,Murzin, A.G.,Vidal, R.,Garringer, H.J.,Ghetti, B.,Scheres, S.H.W.,Goedert, M. (deposition date: 2018-09-26, release date: 2018-10-10, Last modification date: 2024-07-10) |
Primary citation | Falcon, B.,Zhang, W.,Schweighauser, M.,Murzin, A.G.,Vidal, R.,Garringer, H.J.,Ghetti, B.,Scheres, S.H.W.,Goedert, M. Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold. Acta Neuropathol., 136:699-708, 2018 Cited by PubMed: 30276465DOI: 10.1007/s00401-018-1914-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
Download full validation report