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PDB: 36 results

4LN2
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The second SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin
Descriptor: Sorbin and SH3 domain-containing protein 1, proline rich peptide
Authors:Zhao, D, Li, F, Wu, J, Shi, Y, Zhang, Z, Gong, Q.
Deposit date:2013-07-11
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1 Å)
Cite:Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
4LNP
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BU of 4lnp by Molmil
The first SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin
Descriptor: Sorbin and SH3 domain-containing protein 1, Vinculin
Authors:Zhao, D, Li, F, Wu, J, Shi, Y, Zhang, Z, Gong, Q.
Deposit date:2013-07-11
Release date:2014-05-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
3RF3
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BU of 3rf3 by Molmil
Shigella IpaA-VBS3 in complex with human vinculin
Descriptor: CACODYLATE ION, Invasin ipaA, Vinculin
Authors:Park, H, Sharff, A, Izard, T.
Deposit date:2011-04-05
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Novel vinculin binding site of the IpaA invasin of Shigella.
J.Biol.Chem., 286, 2011
1YDI
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BU of 1ydi by Molmil
Human Vinculin Head Domain (VH1, 1-258) in Complex with Human Alpha-Actinin's Vinculin-Binding Site (Residues 731-760)
Descriptor: Alpha-actinin 4, vinculin isoform VCL
Authors:Izard, T.
Deposit date:2004-12-23
Release date:2005-07-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Dynamics of {alpha}-Actinin-Vinculin Interactions.
Mol.Cell.Biol., 14, 2005
3S90
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BU of 3s90 by Molmil
Human vinculin head domain Vh1 (residues 1-252) in complex with murine talin (VBS33; residues 1512-1546)
Descriptor: Talin-1, Vinculin
Authors:Yogesha, S.D, Sharff, A, Bricogne, G, Izard, T.
Deposit date:2011-05-31
Release date:2011-06-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Intermolecular versus intramolecular interactions of the vinculin binding site 33 of talin.
Protein Sci., 20, 2011
3TJ5
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BU of 3tj5 by Molmil
human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-N; residues 412-434) from Rickettsia rickettsii
Descriptor: Antigenic heat-stable 120 kDa protein, GLYCEROL, Vinculin
Authors:Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T.
Deposit date:2011-08-23
Release date:2011-09-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
3MYI
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BU of 3myi by Molmil
Human metavinculin tail domain
Descriptor: Vinculin
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2010-05-10
Release date:2010-05-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A helix replacement mechanism directs metavinculin functions.
Plos One, 5, 2010
4DJ9
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BU of 4dj9 by Molmil
Human vinculin head domain Vh1 (residues 1-258) in complex with the talin vinculin binding site 50 (VBS50, residues 2078-2099)
Descriptor: Talin-1, Vinculin
Authors:Yogesha, S.D, Rangarajan, E.S, Vonrhein, C, Bricogne, G, Izard, T.
Deposit date:2012-02-01
Release date:2012-02-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of vinculin in complex with vinculin binding site 50 (VBS50), the integrin binding site 2 (IBS2) of talin.
Protein Sci., 21, 2012
1RKE
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BU of 1rke by Molmil
Human vinculin head (1-258) in complex with human vinculin tail (879-1066)
Descriptor: VCL protein, Vinculin
Authors:Izard, T, Evans, G, Borgon, R.A, Rush, C.L, Bricogne, G, Bois, P.R.
Deposit date:2003-11-21
Release date:2004-01-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Vinculin activation by talin through helical bundle conversion
Nature, 427, 2004
1SYQ
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BU of 1syq by Molmil
Human vinculin head domain VH1, residues 1-258, in complex with human talin's vinculin binding site 1, residues 607-636
Descriptor: Talin 1, vinculin isoform VCL
Authors:Izard, T, Vonrhein, C.
Deposit date:2004-04-01
Release date:2004-07-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis for amplifying vinculin activation by talin
J.Biol.Chem., 279, 2004
5L0I
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Human metavinculin MVt R975W cardiomyopathy-associated mutant (residues 959-1134)
Descriptor: GLYCEROL, SODIUM ION, Vinculin
Authors:Chinthalapudi, K, Izard, T.
Deposit date:2016-07-27
Release date:2016-08-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016
3VF0
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BU of 3vf0 by Molmil
Raver1 in complex with metavinculin L954 deletion mutant
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Ribonucleoprotein PTB-binding 1, ...
Authors:Lee, J.H, Vonrhein, C, Bricogne, G, Izard, T.
Deposit date:2012-01-09
Release date:2012-07-25
Last modified:2012-09-19
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:The Metavinculin Tail Domain Directs Constitutive Interactions with Raver1 and vinculin RNA.
J.Mol.Biol., 422, 2012
4EHP
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BU of 4ehp by Molmil
Crystal Structure of human vinculin head domain (residues 1-252) in complex with alpha-catenin (residues 277-382)
Descriptor: ACETATE ION, Catenin alpha-1, Vinculin
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2012-04-03
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:alpha-Catenin unfurls upon binding to vinculin
J.Biol.Chem., 287, 2012
1RKC
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BU of 1rkc by Molmil
Human vinculin head (1-258) in complex with talin's vinculin binding site 3 (residues 1944-1969)
Descriptor: Talin, Vinculin
Authors:Izard, T, Evans, G, Borgon, R.A, Rush, C.L, Bricogne, G, Bois, P.R.
Deposit date:2003-11-21
Release date:2004-01-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Vinculin activation by talin through helical bundle conversion
Nature, 427, 2004
2GWW
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BU of 2gww by Molmil
Human vinculin (head domain, Vh1, residues 1-258) in complex with Shigella's IpaA vinculin binding site (residues 602-633)
Descriptor: IpaA, vinculin
Authors:Izard, T.
Deposit date:2006-05-07
Release date:2006-11-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Shigella applies molecular mimicry to subvert vinculin and invade host cells.
J.Cell Biol., 175, 2006
3H2U
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BU of 3h2u by Molmil
Human raver1 RRM1, RRM2, and RRM3 domains in complex with human vinculin tail domain Vt
Descriptor: Raver-1, Vinculin
Authors:Lee, J.H, Rangarajan, E.S, Yogesha, S.D, Izard, T.
Deposit date:2009-04-14
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions
Structure, 17, 2009
5L0D
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BU of 5l0d by Molmil
Human Metavinculin(residues 959-1130) in complex with PIP2
Descriptor: Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Chinthalapudi, K, Izard, T.
Deposit date:2016-07-27
Release date:2016-08-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016
3TJ6
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BU of 3tj6 by Molmil
human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-C; residues 812-835) from Rickettsia rickettsii
Descriptor: Antigenic heat-stable 120 kDa protein, Vinculin
Authors:Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T.
Deposit date:2011-08-23
Release date:2011-09-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
5L0F
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BU of 5l0f by Molmil
Human metavinculin quadruple mutant (residues 959-1134)
Descriptor: GLYCEROL, Vinculin
Authors:Chinthalapudi, K, Izard, T.
Deposit date:2016-07-27
Release date:2016-08-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016
3H2V
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BU of 3h2v by Molmil
Human raver1 RRM1 domain in complex with human vinculin tail domain Vt
Descriptor: Raver-1, Vinculin
Authors:Lee, J.H, Rangarajan, E.S, Yogesha, S.D, Izard, T.
Deposit date:2009-04-14
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions
Structure, 17, 2009
6UPW
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BU of 6upw by Molmil
Metavinculin ABD-F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mei, L, Alushin, G.M.
Deposit date:2019-10-18
Release date:2020-09-30
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular mechanism for direct actin force-sensing by alpha-catenin.
Elife, 9, 2020
5L0H
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BU of 5l0h by Molmil
Human metavinculin MVt cardiomyopathy-associated mutant R975W (residues 959-1134) in complex with PIP2
Descriptor: DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, Vinculin, ...
Authors:Chinthalapudi, K, Izard, T.
Deposit date:2016-07-27
Release date:2016-08-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016
1TR2
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BU of 1tr2 by Molmil
Crystal structure of human full-length vinculin (residues 1-1066)
Descriptor: VINCULIN ISOFORM 1
Authors:Borgon, R.A, Vonrhein, C, Bricogne, G, Bois, P.R, Izard, T.
Deposit date:2004-06-19
Release date:2005-11-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of Human Vinculin
Structure, 12, 2004
6FUY
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BU of 6fuy by Molmil
Crystal structure of human full-length vinculin-T12-A974K (residues 1-1066)
Descriptor: CALCIUM ION, Vinculin
Authors:Chorev, D.S, Volberg, T, Livne, A, Eisenstein, M, Martins, B, Kam, Z, Jockusch, B.M, Medalia, O, Sharon, M, Geiger, B.
Deposit date:2018-02-28
Release date:2018-03-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Conformational states during vinculin unlocking differentially regulate focal adhesion properties.
Sci Rep, 8, 2018
5L0C
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Human metavinculin (residues 959-1134) in complex with PIP2
Descriptor: PHOSPHATE ION, Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Chinthalapudi, K, Izard, T.
Deposit date:2016-07-27
Release date:2016-08-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016

 

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