3RF3

Shigella IpaA-VBS3 in complex with human vinculin

Summary for 3RF3

Related2gww 2hsq 2ibf
DescriptorVinculin, Invasin ipaA, CACODYLATE ION, ... (4 entities in total)
Functional Keywordsalpha-helix bundle domain, cytoskeletal protein, protein-protein interactions, cell adhesion, cytoskeleton, bacterial toxins, pathogen-host interactions, ipaa, talin, f-actin, phosphatidylinositol 4 5-bisphosphate, cytosol, focal adhesion, protein binding-toxin complex, protein binding/toxin
Biological sourceHomo sapiens (human)
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Cellular locationCytoplasm, cytoskeleton P18206
Secreted P18010
Total number of polymer chains4
Total molecular weight64427.94
Authors
Park, H.,Sharff, A.,Izard, T. (deposition date: 2011-04-05, release date: 2011-04-27, Last modification date: 2012-05-23)
Primary citation
Park, H.,Valencia-Gallardo, C.,Sharff, A.,Tran Van Nhieu, G.,Izard, T.
Novel vinculin binding site of the IpaA invasin of Shigella.
J.Biol.Chem., 286:23214-23221, 2011
PubMed: 21525010 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M110.184283
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.61 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.20810.2%0.4%4.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3rf3
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Molmil generated image of 3rf3
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Molmil generated image of 3rf3
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