3RF3
Shigella IpaA-VBS3 in complex with human vinculin
Summary for 3RF3
Entry DOI | 10.2210/pdb3rf3/pdb |
Related | 2gww 2hsq 2ibf |
Descriptor | Vinculin, Invasin ipaA, CACODYLATE ION, ... (4 entities in total) |
Functional Keywords | alpha-helix bundle domain, cytoskeletal protein, protein-protein interactions, cell adhesion, cytoskeleton, bacterial toxins, pathogen-host interactions, ipaa, talin, f-actin, phosphatidylinositol 4 5-bisphosphate, cytosol, focal adhesion, protein binding-toxin complex, protein binding/toxin |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton: P18206 Secreted: P18010 |
Total number of polymer chains | 4 |
Total formula weight | 64427.94 |
Authors | Park, H.,Sharff, A.,Izard, T. (deposition date: 2011-04-05, release date: 2011-04-27, Last modification date: 2023-09-13) |
Primary citation | Park, H.,Valencia-Gallardo, C.,Sharff, A.,Tran Van Nhieu, G.,Izard, T. Novel vinculin binding site of the IpaA invasin of Shigella. J.Biol.Chem., 286:23214-23221, 2011 Cited by PubMed: 21525010DOI: 10.1074/jbc.M110.184283 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.61 Å) |
Structure validation
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