Human vinculin (head domain, Vh1, residues 1-258) in complex with Shigella's IpaA vinculin binding site 2 (residues 565-587)

Summary for 2HSQ

DescriptorVinculin, Invasin ipaA (2 entities in total)
Functional Keywordsprotein complex, cell adhesion, structural protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton P18206
Secreted P18010
Total number of polymer chains2
Total molecular weight32526.44
Izard, T. (deposition date: 2006-07-22, release date: 2006-11-21, Last modification date: 2011-07-13)
Primary citation
Izard, T.,Tran Van Nhieu, G.,Bois, P.R.
Shigella applies molecular mimicry to subvert vinculin and invade host cells.
J.Cell Biol., 175:465-475, 2006
PubMed: 17088427 (PDB entries with the same primary citation)
DOI: 10.1083/jcb.200605091
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers703.2%42.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2hsq
no rotation
Molmil generated image of 2hsq
rotated about x axis by 90°
Molmil generated image of 2hsq
rotated about y axis by 90°
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2019 Protein Data Bank Japan