2HSQ

Human vinculin (head domain, Vh1, residues 1-258) in complex with Shigella's IpaA vinculin binding site 2 (residues 565-587)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Vinculin	polymer	266	30026.6	1	UniProt (P18206) Pfam (PF01044)	Homo sapiens (human)	Metavinculin
2	B (B)	Invasin ipaA	polymer	23	2499.9	1	UniProt (P18010) Pfam (PF17985)	Shigella flexneri	70 kDa antigen

Sequence modifications

A: 2 - 258 (UniProt: P18206)

PDB	External Database	Details
Met -7	-	cloning artifact
Glu -6	-	cloning artifact
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Met 1	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	32526.4
All*	Total formula weight	32526.4

*Water molecules are not included.