2IBF

Human vinculin's head domain (Vh1, residues 1-258) in complex with two vinculin binding sites of Shigella flexneri's IpaA (residues 565-587)

Summary for 2IBF

Related1RKC 1RKE 1SYQ 1YDI 2GWW 2HSQ
DescriptorVinculin, Invasin ipaA (2 entities in total)
Functional Keywordscell adhesion, structural protein
Biological sourceHomo sapiens (human)
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Cellular locationCytoplasm, cytoskeleton P18206
Secreted P18010
Total number of polymer chains3
Total molecular weight35530.8
Authors
Izard, T. (deposition date: 2006-09-11, release date: 2007-09-18, Last modification date: 2011-07-13)
Primary citation
Nhieu, G.T.,Izard, T.
Vinculin binding in its closed conformation by a helix addition mechanism.
Embo J., 26:4588-4596, 2007
PubMed: 17932491 (PDB entries with the same primary citation)
DOI: 10.1038/sj.emboj.7601863
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers532.4%30.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2ibf
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Molmil generated image of 2ibf
rotated about x axis by 90°
Molmil generated image of 2ibf
rotated about y axis by 90°
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