Human vinculin head (1-258) in complex with human vinculin tail (879-1066)

Summary for 1RKE

DescriptorVinculin, VCL protein (3 entities in total)
Functional Keywordscytoskeleton; actin-binding; x-ray crystallography, cell adhesion, structural protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton P18206 P18206
Total number of polymer chains2
Total molecular weight50325.06
Izard, T.,Evans, G.,Borgon, R.A.,Rush, C.L.,Bricogne, G.,Bois, P.R. (deposition date: 2003-11-21, release date: 2004-01-13, Last modification date: 2011-07-13)
Primary citation
Izard, T.,Evans, G.,Borgon, R.A.,Rush, C.L.,Bricogne, G.,Bois, P.R.
Vinculin activation by talin through helical bundle conversion
Nature, 427:171-175, 2004
PubMed: 14702644 (PDB entries with the same primary citation)
DOI: 10.1038/nature02281
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers300.2%12.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload