1RKC

Human vinculin head (1-258) in complex with talin's vinculin binding site 3 (residues 1944-1969)

Summary for 1RKC

• Entry DOI: 10.2210/pdb1rkc/pdb
• Related: 1RKE
• Descriptor: Vinculin, Talin (2 entities in total)
• Functional Keywords: cytoskeleton; actin-binding; x-ray crystallography, cell adhesion, structural protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, cytoskeleton: P18206; Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side: P54939
• Total number of polymer chains: 2
• Total formula weight: 32395.37

Authors

Izard, T.,Evans, G.,Borgon, R.A.,Rush, C.L.,Bricogne, G.,Bois, P.R. (deposition date: 2003-11-21, release date: 2004-01-13, Last modification date: 2024-02-14)

• Primary citation: Izard, T.,Evans, G.,Borgon, R.A.,Rush, C.L.,Bricogne, G.,Bois, P.R.; Vinculin activation by talin through helical bundle conversion; Nature, 427:171-175, 2004; PubMed: 14702644; DOI: 10.1038/nature02281

Experimental method

X-RAY DIFFRACTION (2.7 Å)