1RKC

Human vinculin head (1-258) in complex with talin's vinculin binding site 3 (residues 1944-1969)

Summary for 1RKC

Related1RKE
DescriptorVinculin, Talin (2 entities in total)
Functional Keywordscytoskeleton; actin-binding; x-ray crystallography, cell adhesion, structural protein
Biological sourceHomo sapiens (human)
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Cellular locationCytoplasm, cytoskeleton P18206
Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side P54939
Total number of polymer chains2
Total molecular weight32395.37
Authors
Izard, T.,Evans, G.,Borgon, R.A.,Rush, C.L.,Bricogne, G.,Bois, P.R. (deposition date: 2003-11-21, release date: 2004-01-13, Last modification date: 2011-07-13)
Primary citation
Izard, T.,Evans, G.,Borgon, R.A.,Rush, C.L.,Bricogne, G.,Bois, P.R.
Vinculin activation by talin through helical bundle conversion
Nature, 427:171-175, 2004
PubMed: 14702644 (PDB entries with the same primary citation)
DOI: 10.1038/nature02281
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers762.5%23.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1rkc
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Molmil generated image of 1rkc
rotated about x axis by 90°
Molmil generated image of 1rkc
rotated about y axis by 90°
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