4LNP

The first SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin

Summary for 4LNP

Related4LN2 2MOX
DescriptorSorbin and SH3 domain-containing protein 1, Vinculin (3 entities in total)
Functional Keywordssh3 domain, cell migration, proline rich peptide, focal adhesion, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCell junction, adherens junction Q9BX66
Cytoplasm, cytoskeleton  P18206
Total number of polymer chains2
Total molecular weight8340.57
Authors
Zhao, D.,Li, F.,Wu, J.,Shi, Y.,Zhang, Z.,Gong, Q. (deposition date: 2013-07-11, release date: 2014-05-28, Last modification date: 2014-12-10)
Primary citation
Zhao, D.,Wang, X.,Peng, J.,Wang, C.,Li, F.,Sun, Q.,Zhang, Y.,Zhang, J.,Cai, G.,Zuo, X.,Wu, J.,Shi, Y.,Zhang, Z.,Gong, Q.
Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187:194-205, 2014
PubMed: 24878663 (PDB entries with the same primary citation)
DOI: 10.1016/j.jsb.2014.05.009
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.41 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.207501.6%1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4lnp
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Molmil generated image of 4lnp
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Molmil generated image of 4lnp
rotated about y axis by 90°