3S90

Human vinculin head domain Vh1 (residues 1-252) in complex with murine talin (VBS33; residues 1512-1546)

Summary for 3S90

Related2x0c 1syq 1t01 1rkc 2bif 3rf3
DescriptorVinculin, Talin-1 (3 entities in total)
Functional Keywordsfour-helix bundle, cell adhesion, focal adhesion
Biological sourceHomo sapiens (human)
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Cellular locationCell membrane ; Peripheral membrane protein ; Cytoplasmic side  P18206
Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side  P26039
Total number of polymer chains4
Total molecular weight64738.98
Authors
Yogesha, S.D.,Sharff, A.,Bricogne, G.,Izard, T. (deposition date: 2011-05-31, release date: 2011-06-22, Last modification date: 2017-11-08)
Primary citation
Yogesha, S.D.,Sharff, A.,Bricogne, G.,Izard, T.
Intermolecular versus intramolecular interactions of the vinculin binding site 33 of talin.
Protein Sci., 20:1471-1476, 2011
PubMed: 21648001 (PDB entries with the same primary citation)
DOI: 10.1002/pro.671
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.97 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.221101.9%3.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3s90
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Molmil generated image of 3s90
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Molmil generated image of 3s90
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More Biological unit images

Molmil generated image of 3s90
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Molmil generated image of 3s90
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Molmil generated image of 3s90
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (3s90.pdb1.gz [97.22 KB])
Coordinate files for Biological unit (3s90.pdb2.gz [98.36 KB])
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