4RL5
 
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4RDD
 | | Co-crystal structure of SHP2 in complex with a Cefsulodin derivative | | Descriptor: | 1-({(2R)-4-carboxy-2-[(R)-carboxy{[(2R)-2-phenyl-2-sulfoacetyl]amino}methyl]-3,6-dihydro-2H-1,3-thiazin-5-yl}methyl)pyridinium, Tyrosine-protein phosphatase non-receptor type 11 | | Authors: | Zhang, Z.Y, Yu, Z.H, He, R, Zhang, R.Y. | | Deposit date: | 2014-09-18 | | Release date: | 2015-07-01 | | Last modified: | 2015-12-16 | | Method: | X-RAY DIFFRACTION (1.601 Å) | | Cite: | Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.
ACS Med Chem Lett, 6, 2015
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4WXX
 | | The crystal structure of human DNMT1(351-1600) | | Descriptor: | DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | | Authors: | Zhang, Z.M, Song, J. | | Deposit date: | 2014-11-14 | | Release date: | 2015-07-15 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.622 Å) | | Cite: | Crystal Structure of Human DNA Methyltransferase 1.
J.Mol.Biol., 427, 2015
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6Y6I
 | | lipopolysaccharide outer core galactosyltransferase WaaB and UDP complex | | Descriptor: | Lipopolysaccharide 1,6-galactosyltransferase, URIDINE-5'-DIPHOSPHATE | | Authors: | Zhang, Z.Y, Ashworth, G, Wang, Z.S, Zhu, X.F, Dong, C.J. | | Deposit date: | 2020-02-26 | | Release date: | 2021-03-31 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Structural insights into the lipopolysaccharide outer core galactosyltransferase WaaB
To Be Published
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6Y6G
 | | lipopolysaccharide outer core galactosyltransferase WaaB apo form | | Descriptor: | Lipopolysaccharide 1,6-galactosyltransferase | | Authors: | Zhang, Z.Y, Ashworth, G, Wang, Z.S, Zhu, X.F, Dong, C.J. | | Deposit date: | 2020-02-26 | | Release date: | 2021-03-31 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Structural insights into the lipopolysaccharide outer core galactosyltransferase WaaB
To Be Published
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8GUO
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8GUN
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7V56
 | | Structure of AdaV | | Descriptor: | AdaV, FE (III) ION | | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | | Deposit date: | 2021-08-16 | | Release date: | 2022-08-24 | | Last modified: | 2023-03-01 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis
Acs Catalysis, 12, 2022
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7V52
 | | Structure of AdaV | | Descriptor: | AdaV, FE (III) ION | | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | | Deposit date: | 2021-08-16 | | Release date: | 2022-08-24 | | Last modified: | 2023-03-01 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis
Acs Catalysis, 12, 2022
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7V57
 | | Structure of AdaV | | Descriptor: | 2-OXOGLUTARIC ACID, AdaV, CHLORIDE ION, ... | | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | | Deposit date: | 2021-08-16 | | Release date: | 2022-08-24 | | Last modified: | 2023-03-01 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis
Acs Catalysis, 12, 2022
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7V54
 | | Structure of AdaV | | Descriptor: | AdaV, FE (III) ION | | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | | Deposit date: | 2021-08-16 | | Release date: | 2022-08-24 | | Last modified: | 2023-03-01 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis
Acs Catalysis, 12, 2022
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8BDP
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1EXZ
 | | STRUCTURE OF STEM CELL FACTOR | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, SAMARIUM (III) ION, ... | | Authors: | Zhang, Z, Zhang, R, Joachimiak, A, Schlessinger, J, Kong, X. | | Deposit date: | 2000-05-05 | | Release date: | 2000-07-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activation.
Proc.Natl.Acad.Sci.USA, 97, 2000
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1BG5
 | | CRYSTAL STRUCTURE OF THE ANKYRIN BINDING DOMAIN OF ALPHA-NA,K-ATPASE AS A FUSION PROTEIN WITH GLUTATHIONE S-TRANSFERASE | | Descriptor: | FUSION PROTEIN OF ALPHA-NA,K-ATPASE WITH GLUTATHIONE S-TRANSFERASE | | Authors: | Zhang, Z, Devarajan, P, Morrow, J.S. | | Deposit date: | 1998-06-05 | | Release date: | 1999-01-13 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of the ankyrin-binding domain of alpha-Na,K-ATPase.
J.Biol.Chem., 273, 1998
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8CX5
 | | Crystal Structure of small molecule alpha,beta-ketoamide 4 covalently bound to K-Ras(G12R) | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAGNESIUM ION, ... | | Authors: | Zhang, Z, Morstein, J, Ecker, A, Guiley, K.Z, Shokat, K.M. | | Deposit date: | 2022-05-19 | | Release date: | 2022-08-31 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Chemoselective Covalent Modification of K-Ras(G12R) with a Small Molecule Electrophile.
J.Am.Chem.Soc., 144, 2022
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8GUP
 | | Crystal structure of EsaG from Staphylococcus aureus | | Descriptor: | CITRIC ACID, Type VII secretion system protein EsaG | | Authors: | Zhang, Z.M, Wang, Y.J. | | Deposit date: | 2022-09-13 | | Release date: | 2022-11-09 | | Method: | X-RAY DIFFRACTION (2.298725 Å) | | Cite: | A toxin-deformation dependent inhibition mechanism in the T7SS toxin-antitoxin system of Gram-positive bacteria.
Nat Commun, 13, 2022
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6Y53
 | | human 17S U2 snRNP low resolution part | | Descriptor: | HIV Tat-specific factor 1, Probable ATP-dependent RNA helicase DDX46, Small nuclear ribonucleoprotein E, ... | | Authors: | Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. | | Deposit date: | 2020-02-24 | | Release date: | 2020-06-17 | | Last modified: | 2020-07-22 | | Method: | ELECTRON MICROSCOPY (7.1 Å) | | Cite: | Molecular architecture of the human 17S U2 snRNP.
Nature, 583, 2020
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8QO9
 | | Cryo-EM structure of a human spliceosomal B complex protomer | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ... | | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R. | | Deposit date: | 2023-09-28 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (5.29 Å) | | Cite: | New insights into the functions of B complex proteins revealed by cryo-EM of dimerized
spliceosomes
To Be Published
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6Y5Q
 | | human 17S U2 snRNP | | Descriptor: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... | | Authors: | Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. | | Deposit date: | 2020-02-25 | | Release date: | 2020-06-17 | | Last modified: | 2020-07-22 | | Method: | ELECTRON MICROSCOPY (7.1 Å) | | Cite: | Molecular architecture of the human 17S U2 snRNP.
Nature, 583, 2020
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8Q7N
 | | cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region) | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ... | | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R. | | Deposit date: | 2023-08-16 | | Release date: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | New insights into the functions of B complex proteins revealed by cryo-EM of dimerized spliceosomes
To Be Published
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5LSQ
 | | Ethylene Forming Enzyme from Pseudomonas syringae pv. phaseolicola - I222 crystal form | | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Ethylene Forming Enzyme, ... | | Authors: | Zhang, Z, McDonough, M.A, Schofield, C.J. | | Deposit date: | 2016-09-05 | | Release date: | 2017-04-19 | | Last modified: | 2017-05-10 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8UVK
 | | CosR DNA bound form II | | Descriptor: | DI(HYDROXYETHYL)ETHER, DNA (5'-D(*AP*AP*TP*TP*AP*AP*GP*AP*TP*AP*TP*TP*AP*TP*TP*AP*AP*CP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*GP*TP*TP*AP*AP*TP*AP*AP*TP*AP*TP*CP*TP*TP*AP*AP*TP*T)-3'), ... | | Authors: | Zhang, Z. | | Deposit date: | 2023-11-03 | | Release date: | 2024-01-31 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Structural basis of DNA recognition of the Campylobacter jejuni CosR regulator.
Mbio, 15, 2024
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8UVX
 | | CosR DNA bound form I | | Descriptor: | DNA (5'-D(*AP*TP*AP*TP*CP*TP*TP*AP*AP*TP*TP*TP*TP*GP*GP*TP*TP*AP*AP*TP*A)-3'), DNA (5'-D(*TP*AP*TP*TP*AP*AP*CP*CP*AP*AP*AP*AP*TP*TP*AP*AP*GP*AP*TP*AP*T)-3'), DNA-binding response regulator | | Authors: | Zhang, Z. | | Deposit date: | 2023-11-05 | | Release date: | 2024-01-31 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis of DNA recognition of the Campylobacter jejuni CosR regulator.
Mbio, 15, 2024
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6F57
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5N80
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