3TJ5
human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-N; residues 412-434) from Rickettsia rickettsii
Summary for 3TJ5
Entry DOI | 10.2210/pdb3tj5/pdb |
Related | 1rkc 2gww 2hsq 2ibf 3rf3 3s90 3TJ6 |
Descriptor | Vinculin, Antigenic heat-stable 120 kDa protein, GLYCEROL, ... (4 entities in total) |
Functional Keywords | cytoskeleton, epidemic typhus, sca4, spotted fever, alpha-helix bundle domain, protein-protein interactions, cell adhesion, cytosol, focal adhesion, protein binding-toxin complex, protein binding/toxin |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : P18206 |
Total number of polymer chains | 2 |
Total formula weight | 31469.28 |
Authors | Park, H.,Lee, J.H.,Gouin, E.,Cossart, P.,Izard, T. (deposition date: 2011-08-23, release date: 2011-09-07, Last modification date: 2023-09-13) |
Primary citation | Park, H.,Lee, J.H.,Gouin, E.,Cossart, P.,Izard, T. The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin. J.Biol.Chem., 286:35096-35103, 2011 Cited by PubMed: 21841197DOI: 10.1074/jbc.M111.263855 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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