7BO7
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![BU of 7bo7 by Molmil](/molmil-images/mine/7bo7) | CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJB44355437 | 分子名称: | (2~{R},3~{R},4~{S},5~{R})-2-[(4~{a}~{S},7~{a}~{S})-4-azanyl-1,4,4~{a},7~{a}-tetrahydropyrrolo[2,3-d]pyrimidin-7-yl]-5-(quinolin-7-yloxymethyl)oxolane-3,4-diol, 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Brown, D, Robinson, C, Carr, K.H, Pande, V. | 登録日 | 2021-01-24 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJB44355437 To Be Published
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7QWR
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![BU of 7qwr by Molmil](/molmil-images/mine/7qwr) | Structure of the ribosome-nascent chain containing an ER signal sequence in complex with NAC | 分子名称: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. | 登録日 | 2022-01-25 | 公開日 | 2022-03-09 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
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3CMM
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7QWQ
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![BU of 7qwq by Molmil](/molmil-images/mine/7qwq) | Ternary complex of ribosome nascent chain with SRP and NAC | 分子名称: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. | 登録日 | 2022-01-25 | 公開日 | 2022-03-16 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
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2BTE
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![BU of 2bte by Molmil](/molmil-images/mine/2bte) | Thermus thermophilus Leucyl-tRNA synthetase complexed with a tRNAleu transcript in the post-editing conformation and a post- transfer editing substrate analogue | 分子名称: | 2'-AMINO-2'-DEOXYADENOSINE, AMINOACYL-TRNA SYNTHETASE, LEUCINE, ... | 著者 | Cusack, S, Tukalo, M, Yaremchuk, A, Fukunaga, R, Yokoyama, S. | 登録日 | 2005-05-31 | 公開日 | 2005-09-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The Crystal Structure of Leucyl-tRNA Synthetase Complexed with tRNA(Leu) in the Post-Transfer- Editing Conformation. Nat.Struct.Mol.Biol., 12, 2005
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1QF6
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![BU of 1qf6 by Molmil](/molmil-images/mine/1qf6) | STRUCTURE OF E. COLI THREONYL-TRNA SYNTHETASE COMPLEXED WITH ITS COGNATE TRNA | 分子名称: | ADENOSINE MONOPHOSPHATE, THREONINE TRNA, THREONYL-TRNA SYNTHETASE, ... | 著者 | Sankaranarayanan, R, Dock-Bregeon, A.C, Rees, B, Moras, D. | 登録日 | 1999-04-06 | 公開日 | 1999-05-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The structure of threonyl-tRNA synthetase-tRNA(Thr) complex enlightens its repressor activity and reveals an essential zinc ion in the active site Cell(Cambridge,Mass.), 97, 1999
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1O0C
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7ZR0
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6SWA
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![BU of 6swa by Molmil](/molmil-images/mine/6swa) | |
6WCZ
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![BU of 6wcz by Molmil](/molmil-images/mine/6wcz) | CryoEM structure of full-length ZIKV NS5-hSTAT2 complex | 分子名称: | Non-structural protein 5, Signal transducer and activator of transcription 2, ZINC ION | 著者 | Boxiao, W, Stephanie, T, Kang, Z, Maria, T.S, Jian, F, Jiuwei, L, Linfeng, G, Wendan, R, Yanxiang, C, Ethan, C.V, HeaJin, H, Matthew, J.E, Sean, E.O, Adolfo, G.S, Hong, Z, Rong, H, Jikui, S. | 登録日 | 2020-03-31 | 公開日 | 2020-07-08 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural basis for STAT2 suppression by flavivirus NS5. Nat.Struct.Mol.Biol., 27, 2020
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6J30
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![BU of 6j30 by Molmil](/molmil-images/mine/6j30) | yeast proteasome in Ub-engaged state (C2) | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | 著者 | Cong, Y. | 登録日 | 2019-01-03 | 公開日 | 2019-03-20 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations. Mol. Cell, 73, 2019
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6J2N
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![BU of 6j2n by Molmil](/molmil-images/mine/6j2n) | yeast proteasome in substrate-processing state (C3-b) | 分子名称: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | 著者 | Cong, Y. | 登録日 | 2019-01-02 | 公開日 | 2019-03-20 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | 主引用文献 | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations. Mol. Cell, 73, 2019
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6J2C
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![BU of 6j2c by Molmil](/molmil-images/mine/6j2c) | Yeast proteasome in translocation competent state (C3-a) | 分子名称: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | 著者 | Cong, Y. | 登録日 | 2019-01-01 | 公開日 | 2019-03-13 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations. Mol. Cell, 73, 2019
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8RX0
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![BU of 8rx0 by Molmil](/molmil-images/mine/8rx0) | (NEDD8)-CRL2VHL-MZ1-Brd4BD2-Ub(G76S, K48C)-UBE2R1(C93K, S138C, C191S, C223S)-Ub | 分子名称: | (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-2,3-dihydro-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Cullin-2, Elongin-B, ... | 著者 | Crowe, C, Nakasone, M.A. | 登録日 | 2024-02-05 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | (NEDD8)-CRL2VHL-MZ1-Brd4BD2-Ub(G76S, K48C)-UBE2R1(C93K, S138C, C191S, C223S)-Ub To Be Published
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8S4G
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![BU of 8s4g by Molmil](/molmil-images/mine/8s4g) | Cryo-EM structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1 at 3.2 Angstrom resolution | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | 著者 | Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D. | 登録日 | 2024-02-21 | 公開日 | 2024-03-13 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C-CDH1-EMI1 complex To Be Published
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5GHD
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7JY5
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![BU of 7jy5 by Molmil](/molmil-images/mine/7jy5) | Structure of human p97 in complex with ATPgammaS and Npl4/Ufd1 (masked around p97) | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | 著者 | Pan, M, Yu, Y, Liu, L, Zhao, M. | 登録日 | 2020-08-28 | 公開日 | 2021-01-20 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative. Nat Commun, 12, 2021
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7K59
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![BU of 7k59 by Molmil](/molmil-images/mine/7k59) | Structure of apo VCP hexamer generated from bacterially recombinant VCP/p97 | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | 登録日 | 2020-09-16 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. Iscience, 24, 2021
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7K56
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![BU of 7k56 by Molmil](/molmil-images/mine/7k56) | Structure of VCP dodecamer purified from H1299 cells | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | 登録日 | 2020-09-16 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. Iscience, 24, 2021
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7K57
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![BU of 7k57 by Molmil](/molmil-images/mine/7k57) | Structure of apo VCP dodecamer generated from bacterially recombinant VCP/p97 | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | 登録日 | 2020-09-16 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. Iscience, 24, 2021
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5C9Z
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7L5W
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![BU of 7l5w by Molmil](/molmil-images/mine/7l5w) | p97-R155H mutant dodecamer I | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. | 登録日 | 2020-12-23 | 公開日 | 2021-08-04 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | 主引用文献 | Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes. Int J Mol Sci, 22, 2021
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7L5X
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![BU of 7l5x by Molmil](/molmil-images/mine/7l5x) | p97-R155H mutant dodecamer II | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. | 登録日 | 2020-12-23 | 公開日 | 2021-08-04 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes. Int J Mol Sci, 22, 2021
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4RXZ
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3HCT
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![BU of 3hct by Molmil](/molmil-images/mine/3hct) | Crystal structure of TRAF6 in complex with Ubc13 in the P1 space group | 分子名称: | TNF receptor-associated factor 6, Ubiquitin-conjugating enzyme E2 N, ZINC ION | 著者 | Yin, Q, Lin, S.-C, Lamothe, B, Lu, M, Lo, Y.-C, Hura, G, Zheng, L, Rich, R.L, Campos, A.D, Myszka, D.G, Lenardo, M.J, Darnay, B.G, Wu, H. | 登録日 | 2009-05-06 | 公開日 | 2009-05-26 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | E2 interaction and dimerization in the crystal structure of TRAF6. Nat.Struct.Mol.Biol., 16, 2009
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