7BO7

CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJB44355437

This is a non-PDB format compatible entry.

Summary for 7BO7

• Entry DOI: 10.2210/pdb7bo7/pdb
• Related: 6RLQ
• Descriptor: Protein arginine N-methyltransferase 5, Methylosome protein 50, (2~{R},3~{R},4~{S},5~{R})-2-[(4~{a}~{S},7~{a}~{S})-4-azanyl-1,4,4~{a},7~{a}-tetrahydropyrrolo[2,3-d]pyrimidin-7-yl]-5-(quinolin-7-yloxymethyl)oxolane-3,4-diol, ... (7 entities in total)
• Functional Keywords: complex inhibitor bound prmt5 mep50, translocase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 112277.80

Authors

Brown, D.,Robinson, C.,Carr, K.H.,Pande, V. (deposition date: 2021-01-24, release date: 2022-03-02, Last modification date: 2024-01-31)

• Primary citation: Brown, D.,Robinson, C.,Carr, K.H.,Pande, V.; CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJB44355437; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.83 Å)