8S4G

Cryo-EM structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1 at 3.2 Angstrom resolution

Summary for 8S4G

• Entry DOI: 10.2210/pdb8s4g/pdb
• Related: 7QE7 8PKP
• EMDB information: 19711
• Descriptor: Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 13, Anaphase-promoting complex subunit 16, ... (17 entities in total)
• Functional Keywords: apc/c, cyclosome, cdc20, cdh1, ubiquitination, emi1, mitosis, cell cycle
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 21
• Total formula weight: 1279091.33

Authors

Hoefler, A.,Yu, J.,Chang, L.,Zhang, Z.,Yang, J.,Boland, A.,Barford, D. (deposition date: 2024-02-21, release date: 2024-03-13, Last modification date: 2024-05-22)

• Primary citation: Hoefler, A.,Yu, J.,Chang, L.,Zhang, Z.,Yang, J.,Boland, A.,Barford, D.; New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C-CDH1-EMI1 complex; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.2 Å)