7ZR0
CryoEM structure of HSP90-CDC37-BRAF(V600E) complex.
Summary for 7ZR0
| Entry DOI | 10.2210/pdb7zr0/pdb |
| EMDB information | 14875 |
| Descriptor | Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, Serine/threonine-protein kinase B-raf, ... (4 entities in total) |
| Functional Keywords | complex, protein binding, chaperone |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 311249.62 |
| Authors | Oberoi, J.,Pearl, L.H. (deposition date: 2022-05-03, release date: 2022-12-14, Last modification date: 2023-01-11) |
| Primary citation | Oberoi, J.,Guiu, X.A.,Outwin, E.A.,Schellenberger, P.,Roumeliotis, T.I.,Choudhary, J.S.,Pearl, L.H. HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13:7343-7343, 2022 Cited by PubMed: 36446791DOI: 10.1038/s41467-022-35143-2 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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