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7JY5

Structure of human p97 in complex with ATPgammaS and Npl4/Ufd1 (masked around p97)

Summary for 7JY5
Entry DOI10.2210/pdb7jy5/pdb
EMDB information21824 21825 21826 22521
DescriptorTransitional endoplasmic reticulum ATPase, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (3 entities in total)
Functional Keywordsaaa+ atpase chaperon protein homeostasis, translocase
Biological sourceHomo sapiens (Human)
Total number of polymer chains6
Total formula weight543191.54
Authors
Pan, M.,Yu, Y.,Liu, L.,Zhao, M. (deposition date: 2020-08-28, release date: 2021-01-20, Last modification date: 2024-03-06)
Primary citationPan, M.,Zheng, Q.,Yu, Y.,Ai, H.,Xie, Y.,Zeng, X.,Wang, C.,Liu, L.,Zhao, M.
Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative.
Nat Commun, 12:121-121, 2021
Cited by
PubMed: 33402676
DOI: 10.1038/s41467-020-20359-x
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.89 Å)
Structure validation

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