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5F5O
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BU of 5f5o by Molmil
Crystal structure of Marburg virus nucleoprotein core domain bound to VP35 regulation peptide
Descriptor: Nucleoprotein, Peptide from Polymerase cofactor VP35, SULFATE ION
Authors:Guo, Y, Liu, B.C, Liu, X, Li, G.B, Wang, W.M, Dong, S.S, Wang, W.J.
Deposit date:2015-12-04
Release date:2017-05-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insight into Nucleoprotein Conformation Change Chaperoned by VP35 Peptide in Marburg Virus
J. Virol., 91, 2017
3S0Z
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BU of 3s0z by Molmil
Crystal structure of New Delhi Metallo-beta-lactamase (NDM-1)
Descriptor: Metallo-beta-lactamase, ZINC ION
Authors:Guo, Y, Wang, J, Niu, G.J, Shui, W.Q, Sun, Y.N, Lou, Z.Y, Rao, Z.H.
Deposit date:2011-05-13
Release date:2011-06-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A structural view of the antibiotic degradation enzyme NDM-1 from a superbug.
Protein Cell, 2011
3RDR
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BU of 3rdr by Molmil
Structure of the catalytic domain of XlyA
Descriptor: CHLORIDE ION, N-acetylmuramoyl-L-alanine amidase XlyA, ZINC ION
Authors:Low, L.Y, Liddington, R.C.
Deposit date:2011-04-01
Release date:2011-08-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Role of net charge on catalytic domain and influence of cell wall binding domain on bactericidal activity, specificity, and host range of phage lysins.
J.Biol.Chem., 286, 2011
3TOA
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BU of 3toa by Molmil
Human MOF crystal structure with active site lysine partially acetylated
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, ZINC ION, ...
Authors:Yuan, H, Ding, E.C, Marmorstein, R.
Deposit date:2011-09-04
Release date:2011-11-09
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.004 Å)
Cite:MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J., 31, 2011
3TO6
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BU of 3to6 by Molmil
Crystal structure of yeast Esa1 HAT domain complexed with H4K16CoA bisubstrate inhibitor
Descriptor: CARBOXYMETHYL COENZYME *A, Histone H4, Histone acetyltransferase ESA1
Authors:Yuan, H, Ding, E.C, Marmorstein, R.
Deposit date:2011-09-04
Release date:2011-11-09
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J., 31, 2011
3U3I
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BU of 3u3i by Molmil
A RNA binding protein from Crimean-Congo hemorrhagic fever virus
Descriptor: Nucleocapsid protein
Authors:Guo, Y, Wang, W.M, Ji, W, Deng, M, Sun, Y.N, Lou, Z.Y, Rao, Z.H.
Deposit date:2011-10-06
Release date:2012-03-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Crimean-Congo hemorrhagic fever virus nucleoprotein reveals endonuclease activity in bunyaviruses
Proc.Natl.Acad.Sci.USA, 109, 2012
5WUF
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BU of 5wuf by Molmil
Structural basis for conductance through TRIC cation channels
Descriptor: CADMIUM ION, Putative membrane protein
Authors:Mao, Y, Gao, F, Su, M, Wang, X.H, Zeng, Y, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2016-12-17
Release date:2017-08-09
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Structural basis for conductance through TRIC cation channels.
Nat Commun, 8, 2017
5WUC
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BU of 5wuc by Molmil
Structural basis for conductance through TRIC cation channels
Descriptor: SODIUM ION, Uncharacterized protein
Authors:Su, M, Gao, F, Mao, Y, Li, D.L, Guo, Y.Z, Wang, X.H, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2016-12-17
Release date:2017-07-12
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for conductance through TRIC cation channels.
Nat Commun, 8, 2017
5WUD
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BU of 5wud by Molmil
Structural basis for conductance through TRIC cation channels
Descriptor: MAGNESIUM ION, Uncharacterized protein
Authors:Su, M, Gao, F, Mao, Y, Li, D.L, Guo, Y.Z, Wang, X.H, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2016-12-17
Release date:2017-06-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for conductance through TRIC cation channels.
Nat Commun, 8, 2017
5WUE
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BU of 5wue by Molmil
Structural basis for conductance through TRIC cation channels
Descriptor: SULFATE ION, Uncharacterized protein
Authors:Su, M, Gao, F, Mao, Y, Li, D.L, Guo, Y.Z, Wang, X.H, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2016-12-17
Release date:2017-06-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for conductance through TRIC cation channels.
Nat Commun, 8, 2017
5WYG
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BU of 5wyg by Molmil
The crystal structure of the apo form of Mtb MazF
Descriptor: Probable endoribonuclease MazF7
Authors:Xie, W, Chen, R, Tu, J.
Deposit date:2017-01-13
Release date:2017-04-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.356 Å)
Cite:Structure of the MazF-mt9 toxin, a tRNA-specific endonuclease from Mycobacterium tuberculosis
Biochem. Biophys. Res. Commun., 486, 2017
3O2F
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BU of 3o2f by Molmil
Structure of the N-domain of GRP94 bound to the HSP90 inhibitor PU-H54
Descriptor: 8-[(2,4-dimethylphenyl)sulfanyl]-3-pent-4-yn-1-yl-3H-purin-6-amine, Endoplasmin, GLYCEROL, ...
Authors:Seidler, P.M, Gewirth, D.T.
Deposit date:2010-07-22
Release date:2011-10-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2.
Nat.Chem.Biol., 9, 2013
3O0I
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BU of 3o0i by Molmil
Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor PU-H54
Descriptor: 8-[(2,4-dimethylphenyl)sulfanyl]-3-pent-4-yn-1-yl-3H-purin-6-amine, HSP90AA1 protein
Authors:Seidler, P.M, Gewirth, D.T.
Deposit date:2010-07-19
Release date:2011-10-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2.
Nat.Chem.Biol., 9, 2013
3P53
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BU of 3p53 by Molmil
Structure of fascin
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, DODECAETHYLENE GLYCOL, Fascin, ...
Authors:Jansen, S, Dominguez, R.
Deposit date:2010-10-07
Release date:2011-06-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of actin filament bundling by fascin.
J.Biol.Chem., 286, 2011
5XJZ
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BU of 5xjz by Molmil
Structure of DNA1-Ag complex
Descriptor: DNA (5'-D(*GP*CP*AP*CP*GP*CP*GP*C)-3'), SILVER ION, SPERMINE
Authors:Liu, H.H, Gan, J.H.
Deposit date:2017-05-04
Release date:2017-12-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:A DNA Structure Containing AgI -Mediated G:G and C:C Base Pairs
Angew. Chem. Int. Ed. Engl., 56, 2017
5XM2
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BU of 5xm2 by Molmil
Human N-terminal domain of FACT complex subunit SPT16
Descriptor: DI(HYDROXYETHYL)ETHER, FACT complex subunit SPT16, GLYCEROL
Authors:Xu, S, Li, H, Dou, Y, Chen, Y, Jiang, H, Lu, D, Wang, M, Su, D.
Deposit date:2017-05-12
Release date:2018-05-16
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.187 Å)
Cite:The structural basis of human Spt16 N-terminal domain interaction with histone (H3-H4)2tetramer.
Biochem.Biophys.Res.Commun., 508, 2019
4JS0
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BU of 4js0 by Molmil
Complex of Cdc42 with the CRIB-PR domain of IRSp53
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Brain-specific angiogenesis inhibitor 1-associated protein 2, Cell division control protein 42 homolog, ...
Authors:Kast, D.J, Dominguez, R.
Deposit date:2013-03-22
Release date:2014-03-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors.
Nat.Struct.Mol.Biol., 21, 2014
4Q2V
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BU of 4q2v by Molmil
Crystal Structure of Ricin A chain complexed with Baicalin inhibitor
Descriptor: 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, Ricin
Authors:Deng, X, Li, X, Dong, J, Chen, Y.
Deposit date:2014-04-10
Release date:2015-04-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Baicalin inhibits the lethality of ricin in mice by inducing protein oligomerization.
J.Biol.Chem., 290, 2015
5ZFZ
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BU of 5zfz by Molmil
Crystal structure of human DUX4 homeodomains bound to A12T DNA mutant
Descriptor: DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*TP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*AP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4
Authors:Li, Y.Y, Wu, B.X, Gan, J.H.
Deposit date:2018-03-07
Release date:2018-10-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun., 505, 2018
5ZFW
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BU of 5zfw by Molmil
Crystal structure of human DUX4 homeodomains bound to A11G DNA mutant
Descriptor: DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*GP*AP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*TP*CP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4
Authors:Li, Y.Y, Wu, B.X, Gan, J.H.
Deposit date:2018-03-07
Release date:2018-10-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun., 505, 2018
5ZFY
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BU of 5zfy by Molmil
Crystal structure of human DUX4 homeodomains bound to A12C DNA mutant
Descriptor: DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*CP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*GP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4
Authors:Li, Y.Y, Wu, B.X, Gan, J.H.
Deposit date:2018-03-07
Release date:2018-10-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun., 505, 2018
5Z6Z
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BU of 5z6z by Molmil
Crystal structure of human DUX4 homeodomains bound to DNA
Descriptor: DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*AP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4
Authors:Li, Y.Y, Wu, B.X, Gan, J.H.
Deposit date:2018-01-26
Release date:2018-10-31
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun., 505, 2018
4K17
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BU of 4k17 by Molmil
Crystal Structure of mouse CARMIL residues 1-668
Descriptor: CHLORIDE ION, GAMMA-AMINO-BUTANOIC ACID, Leucine-rich repeat-containing protein 16A, ...
Authors:Zwolak, A, Dominguez, R.
Deposit date:2013-04-04
Release date:2013-10-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.895 Å)
Cite:CARMIL leading edge localization depends on a non-canonical PH domain and dimerization.
Nat Commun, 4, 2013
4J4L
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BU of 4j4l by Molmil
Modular evolution and design of the protein binding interface
Descriptor: Interleukin-6, Internalin B,REPEAT MODULES,Variable lymphocyte receptor B
Authors:Cheong, H.K, Kim, H.J.
Deposit date:2013-02-07
Release date:2014-02-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Modular evolution and design of the protein binding interface
To be Published
3BYV
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BU of 3byv by Molmil
Crystal structure of Toxoplasma gondii specific rhoptry antigen kinase domain
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Rhoptry kinase
Authors:Wernimont, A.K, Lunin, V.V, Yang, C, Lew, J, Kozieradzki, I, Lin, Y.H, Sun, X, Khuu, C, Zhao, Y, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bochkarev, A, Hui, R, Sibley, D, Qiu, W, Structural Genomics Consortium (SGC)
Deposit date:2008-01-16
Release date:2008-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Novel structural and regulatory features of rhoptry secretory kinases in Toxoplasma gondii.
Embo J., 28, 2009

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