5Z6Z

Crystal structure of human DUX4 homeodomains bound to DNA

Summary for 5Z6Z

• Entry DOI: 10.2210/pdb5z6z/pdb
• Descriptor: Double homeobox protein 4, DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*AP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), ... (4 entities in total)
• Functional Keywords: homeodomains, dux4, complex, dna recognition, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 29375.72

Authors

Li, Y.Y.,Wu, B.X.,Gan, J.H. (deposition date: 2018-01-26, release date: 2018-10-31, Last modification date: 2024-03-27)

• Primary citation: Li, Y.,Wu, B.,Liu, H.,Gao, Y.,Yang, C.,Chen, X.,Zhang, J.,Chen, Y.,Gu, Y.,Li, J.,Ma, J.,Gan, J.; Structural basis for multiple gene regulation by human DUX4.; Biochem. Biophys. Res. Commun., 505:1161-1167, 2018; PubMed: 30322619; DOI: 10.1016/j.bbrc.2018.10.056

Experimental method

X-RAY DIFFRACTION (2.301 Å)