3TOA

Human MOF crystal structure with active site lysine partially acetylated

Summary for 3TOA

Entry DOI	10.2210/pdb3toa/pdb
Related	3TO6 3TO7 3TO9 3TOB
Descriptor	histone acetyltransferase MYST1, ZINC ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	myst protein, hat domain, zinc finger, transferase
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q9H7Z6
Total number of polymer chains	1
Total formula weight	36036.57
Authors	Yuan, H.,Ding, E.C.,Marmorstein, R. (deposition date: 2011-09-04, release date: 2011-11-09, Last modification date: 2023-12-06)
Primary citation	Yuan, H.,Rossetto, D.,Mellert, H.,Dang, W.,Srinivasan, M.,Johnson, J.,Hodawadekar, S.,Ding, E.C.,Speicher, K.,Abshiru, N.,Perry, R.,Wu, J.,Yang, C.,Zheng, Y.G.,Speicher, D.W.,Thibault, P.,Verreault, A.,Johnson, F.B.,Berger, S.L.,Sternglanz, R.,McMahon, S.B.,Cote, J.,Marmorstein, R. MYST protein acetyltransferase activity requires active site lysine autoacetylation. Embo J., 31:58-70, 2011 Cited by PubMed: 22020126 DOI: 10.1038/emboj.2011.382 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.004 Å)

Structure validation