3TOA

Human MOF crystal structure with active site lysine partially acetylated

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	histone acetyltransferase MYST1	polymer	303	35776.1	1	UniProt (Q9H7Z6) Pfam (PF17772) Pfam (PF01853)	Homo sapiens (human)	MYST-1, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1, hMOF
2	B (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
3	C, D (A)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	E, F (A)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)

Sequence modifications

A: 177 - 458 (UniProt: Q9H7Z6)

PDB	External Database	Details
His 156	-	expression tag
His 157	-	expression tag
His 158	-	expression tag
His 159	-	expression tag
His 160	-	expression tag
His 161	-	expression tag
Asp 162	-	expression tag
Tyr 163	-	expression tag
Asp 164	-	expression tag
Ile 165	-	expression tag
Pro 166	-	expression tag
Thr 167	-	expression tag
Thr 168	-	expression tag
Glu 169	-	expression tag
Asn 170	-	expression tag
Leu 171	-	expression tag
Tyr 172	-	expression tag
Phe 173	-	expression tag
Gln 174	-	expression tag
Gly 175	-	expression tag
Ser 176	-	expression tag
Aly 274	Lys 274	microheterogeneity

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	35776.1
Non-Polymers*	Number of molecules	5
	Total formula weight	260.5
All*	Total formula weight	36036.6

*Water molecules are not included.