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5ZFW

Crystal structure of human DUX4 homeodomains bound to A11G DNA mutant

Summary for 5ZFW
Entry DOI10.2210/pdb5zfw/pdb
DescriptorDouble homeobox protein 4-like protein 4, DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*GP*AP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*TP*CP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), ... (4 entities in total)
Functional Keywordshomeodomains, dux4, dna recognition, transcription-dna complex, transcription/dna
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains3
Total formula weight29037.36
Authors
Li, Y.Y.,Wu, B.X.,Gan, J.H. (deposition date: 2018-03-07, release date: 2018-10-31, Last modification date: 2023-11-22)
Primary citationLi, Y.,Wu, B.,Liu, H.,Gao, Y.,Yang, C.,Chen, X.,Zhang, J.,Chen, Y.,Gu, Y.,Li, J.,Ma, J.,Gan, J.
Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun., 505:1161-1167, 2018
Cited by
PubMed: 30322619
DOI: 10.1016/j.bbrc.2018.10.056
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.103 Å)
Structure validation

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