4Q2V

Crystal Structure of Ricin A chain complexed with Baicalin inhibitor

Summary for 4Q2V

Entry DOI	10.2210/pdb4q2v/pdb
Descriptor	Ricin, 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid (3 entities in total)
Functional Keywords	mixed alpha/beta structure, ribosome-inactivating, baicalin complex, ribosome, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Ricinus communis (Castor bean)
Total number of polymer chains	1
Total formula weight	31701.57
Authors	Deng, X.,Li, X.,Dong, J.,Chen, Y. (deposition date: 2014-04-10, release date: 2015-04-15, Last modification date: 2023-11-08)
Primary citation	Dong, J.,Zhang, Y.,Chen, Y.,Niu, X.,Zhang, Y.,Li, R.,Yang, C.,Wang, Q.,Li, X.,Deng, X. Baicalin inhibits the lethality of ricin in mice by inducing protein oligomerization. J.Biol.Chem., 290:12899-12907, 2015 Cited by PubMed: 25847243 DOI: 10.1074/jbc.M114.632828 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.198 Å)

Structure validation