5ZFY
Crystal structure of human DUX4 homeodomains bound to A12C DNA mutant
Summary for 5ZFY
Entry DOI | 10.2210/pdb5zfy/pdb |
Descriptor | Double homeobox protein 4-like protein 4, DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*CP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*GP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), ... (4 entities in total) |
Functional Keywords | homeodomains, dux4, dna recognition, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 29037.36 |
Authors | |
Primary citation | Li, Y.,Wu, B.,Liu, H.,Gao, Y.,Yang, C.,Chen, X.,Zhang, J.,Chen, Y.,Gu, Y.,Li, J.,Ma, J.,Gan, J. Structural basis for multiple gene regulation by human DUX4. Biochem. Biophys. Res. Commun., 505:1161-1167, 2018 Cited by PubMed: 30322619DOI: 10.1016/j.bbrc.2018.10.056 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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