5ZFY

Crystal structure of human DUX4 homeodomains bound to A12C DNA mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Double homeobox protein 4-like protein 4	polymer	149	17386.8	1	UniProt (P0CJ87) Pfam (PF00046) UniProt (by SIFTS) (Q9UBX2)	Homo sapiens (Human)	DUX4
2	B (D)	DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*CP*TP*CP*AP*CP*AP*CP*C)-3')	polymer	19	5638.7	1		synthetic construct
3	C (E)	DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*GP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3')	polymer	19	6011.9	1		synthetic construct
4	D, E, F (A, D, E)	water	water		18.0	167	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	29037.4
All*	Total formula weight	29037.4

*Water molecules are not included.