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2N6F
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STRUCTURE OF PLEIOTROPHIN
Descriptor:Pleiotrophin
Authors:Ryan, E.O., Shen, D., Wang, X.
Deposit date:2015-08-20
Release date:2016-04-20
Last modified:2016-05-04
Method:SOLUTION NMR
Cite:Structural studies reveal an important role for the pleiotrophin C-terminus in mediating interactions with chondroitin sulfate.
Febs J., 283, 2016
4CPE
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WILD-TYPE STREPTAVIDIN IN COMPLEX WITH LOVE-HATE LIGAND 1 (LH1)
Descriptor:STREPTAVIDIN, (3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4- d]imidazolidin-4-yl]-N-{2-[(2,6- diphenylphenyl)formamido]ethyl}pentanamide
Authors:Fairhead, M., Shen, D., Chan, L.K.M., Lowe, E.D., Donohoe, T.J., Howarth, M.
Deposit date:2014-02-06
Release date:2014-08-06
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (1.06 Å)
Cite:Love-Hate Ligands for High Resolution Analysis of Strain in Ultra-Stable Protein/Small Molecule Interaction.
Bioorg.Med.Chem., 22, 2014
4CPF
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WILD-TYPE STREPTAVIDIN IN COMPLEX WITH LOVE-HATE LIGAND 3 (LH3)
Descriptor:STREPTAVIDIN, methyl 4-(2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H- thieno[3,4-d]imidazolidin-4-yl]pentanehydrazido}-3- [4-(methoxycarbonyl)phenyl]phenyl)benzoate
Authors:Fairhead, M., Shen, D., Chan, L.K.M., Lowe, E.D., Donohoe, T.J., Howarth, M.
Deposit date:2014-02-06
Release date:2014-08-06
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Love-Hate Ligands for High Resolution Analysis of Strain in Ultra-Stable Protein/Small Molecule Interaction.
Bioorg.Med.Chem., 22, 2014
4CPH
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TRANS-DIVALENT STREPTAVIDIN WITH LOVE-HATE LIGAND 4
Descriptor:STREPTAVIDIN, 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4- d]imidazolidin-4-yl]-N'-{2,6-bis[4-(morpholine-4- sulfonyl)phenyl]phenyl}pentanehydrazide
Authors:Fairhead, M., Shen, D., Chan, L.K.M., Lowe, E.D., Donohoe, T.J., Howarth, M.
Deposit date:2014-02-06
Release date:2014-08-06
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Love-Hate Ligands for High Resolution Analysis of Strain in Ultra-Stable Protein/Small Molecule Interaction.
Bioorg.Med.Chem., 22, 2014
4CPI
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STREPTAVIDIN A86D MUTANT WITH LOVE-HATE LIGAND 4
Descriptor:STREPTAVIDIN, 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4- d]imidazolidin-4-yl]-N'-{2,6-bis[4-(morpholine-4- sulfonyl)phenyl]phenyl}pentanehydrazide, DI(HYDROXYETHYL)ETHER, ...
Authors:Fairhead, M., Shen, D., Chan, L.K.M., Lowe, E.D., Donohoe, T.J., Howarth, M.
Deposit date:2014-02-06
Release date:2014-08-06
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Love-Hate Ligands for High Resolution Analysis of Strain in Ultra-Stable Protein/Small Molecule Interaction.
Bioorg.Med.Chem., 22, 2014
2VSN
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STRUCTURE AND TOPOLOGICAL ARRANGEMENT OF AN O-GLCNAC TRANSFERASE HOMOLOG: INSIGHT INTO MOLECULAR CONTROL OF INTRACELLULAR GLYCOSYLATION
Descriptor:XCOGT, URIDINE-5'-DIPHOSPHATE
Authors:Martinez-Fleites, C., Macauley, M.S., He, Y., Shen, D., Vocadlo, D., Davies, G.J.
Deposit date:2008-04-28
Release date:2008-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of an O-Glcnac Transferase Homolog Provides Insight Into Intracellular Glycosylation.
Nat.Struct.Mol.Biol., 15, 2008
4D3E
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TETRAMER OF IPAD, MODIFIED FROM 2J0O, FITTED INTO NEGATIVE STAIN ELECTRON MICROSCOPY RECONSTRUCTION OF THE WILD TYPE TIP COMPLEX FROM THE TYPE III SECRETION SYSTEM OF SHIGELLA FLEXNERI
Descriptor:INVASIN IPAD
Authors:Cheung, M., Shen, D.-K., Makino, F., Kato, T., Roehrich, D., Martinez-Argudo, I., Walker, M.L., Murillo, I., Liu, X., Pain, M., Brown, J., Frazer, G., Mantell, J., Mina, P., Todd, T., Sessions, R.B., Namba, K., Blocker, A.J.
Deposit date:2014-10-21
Release date:2014-12-10
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (2.12 Å)
Cite:Three-Dimensional Electron Microscopy Reconstruction and Cysteine-Mediated Crosslinking Provide a Model of the T3Ss Needle Tip Complex.
Mol.Microbiol., 95, 2015
5Y9O
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THE APO STRUCTURE OF LEGIONELLA PNEUMOPHILA WIPA
Descriptor:WipA, IODIDE ION
Authors:Xie, W., Jia, Q.
Deposit date:2017-08-26
Release date:2018-05-16
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.554 Å)
Cite:Legionella pneumophila effector WipA, a bacterial PPP protein phosphatase with PTP activity
Acta Biochim. Biophys. Sin. (Shanghai), 50, 2018
6NXH
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CRYSTAL STRUCTURE OF RAR-RELATED ORPHAN RECEPTOR C (NHIS- RORGT(244-487)-L6-SRC1(678-692)) IN COMPLEX WITH A PHENYL (3-PHENYLPYRROLIDIN-3-YL)SULFONE INHIBITOR
Descriptor:Nuclear receptor ROR-gamma, Nuclear receptor coactivator 1 chimera, 1-(4-{(3R)-3-[(4-fluorophenyl)sulfonyl]-3-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]pyrrolidine-1-carbonyl}piperazin-1-yl)ethan-1-one, ...
Authors:Sack, J.
Deposit date:2019-02-08
Release date:2019-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORgammat Inverse Agonists
Acs Med.Chem.Lett., 2019