7Y35

Cryo-EM structure of the Abaloparatide-bound human PTH1R-Gs complex

Summary for 7Y35

• Entry DOI: 10.2210/pdb7y35/pdb
• EMDB information: 33588
• Descriptor: Parathyroid hormone/parathyroid hormone-related peptide receptor, Abaloparatide, Isoform Gnas-2 of Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... (6 entities in total)
• Functional Keywords: abaloparatide, pth1r, cryo-em structure, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 192768.79

Authors

Zhai, X.,Mao, C.,Shen, Q.,Zang, S.,Shen, D.,Zhang, H.,Chen, Z.,Wang, G.,Zhang, C.,Zhang, Y.,Liu, Z. (deposition date: 2022-06-09, release date: 2023-07-05)

• Primary citation: Zhai, X.,Mao, C.,Shen, Q.,Zang, S.,Shen, D.,Zhang, H.,Chen, Z.,Wang, G.,Zhang, C.,Zhang, Y.,Liu, Z.; Cryo-EM structure of the Abaloparatide-bound human PTH1R-Gs complex; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.9 Å)