8JV7

Cryo-EM structure of the panda P2X7 receptor in complex with PPADS

Summary for 8JV7

• Entry DOI: 10.2210/pdb8jv7/pdb
• EMDB information: 36670
• Descriptor: P2X purinoceptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(E)-[4-methanoyl-6-methyl-5-oxidanyl-3-(phosphonooxymethyl)pyridin-2-yl]diazenyl]benzene-1,3-disulfonic acid, ... (4 entities in total)
• Functional Keywords: channel, transport protein
• Biological source: Ailuropoda melanoleuca (giant panda)
• Total number of polymer chains: 3
• Total formula weight: 119010.08

Authors

Sheng, D.,Hattori, M. (deposition date: 2023-06-27, release date: 2023-11-29, Last modification date: 2024-04-24)

• Primary citation: Sheng, D.,Yue, C.,Jin, F.,Wang, Y.,Ichikawa, M.,Yu, Y.,Guo, C.R.,Hattori, M.; Structural insights into the orthosteric inhibition of P2X receptors by non-ATP-analog antagonists; Elife, 2023; DOI: 10.7554/eLife.92829.1

Experimental method

ELECTRON MICROSCOPY (3.6 Å)