8JV7
Cryo-EM structure of the panda P2X7 receptor in complex with PPADS
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | P2X purinoceptor | polymer | 342 | 38716.2 | 3 | UniProt (D2GVW0) Pfam (PF00864) UniProt (by SIFTS) (G1M6C4) In PDB | Ailuropoda melanoleuca (giant panda) | |
2 | A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
3 | A, B, C | 4-[(E)-[4-methanoyl-6-methyl-5-oxidanyl-3-(phosphonooxymethyl)pyridin-2-yl]diazenyl]benzene-1,3-disulfonic acid | non-polymer | 511.4 | 3 | Chemie (UO6) | |||
4 | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A, B, C: 23 - 359 (UniProt: D2GVW0)
PDB | External Database | Details |
---|---|---|
Gly 21 | - | expression tag |
Ser 22 | - | expression tag |
Ala 35 | Val 35 | engineered mutation |
Ala 125 | Arg 125 | engineered mutation |
Lys 174 | Glu 174 | engineered mutation |
Ser 241 | Asn 241 | engineered mutation |
Ser 284 | Asn 284 | engineered mutation |
Ala 360 | - | expression tag |
Ser 361 | - | expression tag |
Ser 362 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 116148.7 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 2861.4 | |
All* | Total formula weight | 119010.1 |